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Image Unavailable-BOSSBS-1012R-A350

Anti-BMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-1012R-A350)
Dodavatel: Bioss
Popis: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1012R-A647

Anti-BMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-1012R-A647)
Dodavatel: Bioss
Popis: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1012R-HRP

Anti-BMP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-1012R-HRP)
Dodavatel: Bioss
Popis: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13357R-HRP

Anti-ADRM1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-13357R-HRP)
Dodavatel: Bioss
Popis: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13357R-A647

Anti-ADRM1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-13357R-A647)
Dodavatel: Bioss
Popis: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7121R-A680

Anti-Rad23 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-7121R-A680)
Dodavatel: Bioss
Popis: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7121R-A750

Anti-Rad23 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-7121R-A750)
Dodavatel: Bioss
Popis: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13691R

Anti-MS4A15 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-13691R)
Dodavatel: Bioss
Popis: MS4A (membrane-spanning 4-domain family, subfamily A) is a large family of proteins that includes at least 26 members in mouse and humans. Flanked by amino- and carboxyl- cytoplasmic regions, MS4A family members contain four highly conserved transmembrane domains. CD20, the most well-known MS4A family member, is a B-cell-specific molecule that functions as a calcium-permeable cation channel and is known to accelerate the G0 to G1 progression induced by IGF-1. MS4A15 (membrane-spanning 4-domains, subfamily A, member 15) is a 240 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding MS4A15 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7121R-A647

Anti-RAD23 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-7121R-A647)
Dodavatel: Bioss
Popis: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9609R

Anti-RBM26 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-9609R)
Dodavatel: Bioss
Popis: Proteins containing RNA recognition motifs, including various hnRNP proteins, are implicated in the regulation of alternative splicing and protein components of snRNPs. The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif that have been suggested to play a role in the modulation of apoptosis. RBM26 (RNA binding motif protein 26), whose alternative names include CTCL tumor antigen se70-2, C13orf10, ARRS2, SE70-2, ZC3H17, PRO1777, FLJ20957, RP11-255E21.1, MGC133295 or MGC133296, is a 1,007 amino acid protein with six isoforms which result due to alternative splicing. RBM26 also contains one C3H1-type zinc finger and two RRM (RNA recognition motif) domains. The gene encoding RBM26 maps to human chromosome 13q31.1.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13569R

Anti-ZBTB26 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-13569R)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 26 (ZBTB26), also known as ZNF481, is a 441 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB26 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB26 functions as a transcription regulator.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7121R-A350

Anti-RAD23 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-7121R-A350)
Dodavatel: Bioss
Popis: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7121R-FITC

Anti-RAD23 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-7121R-FITC)
Dodavatel: Bioss
Popis: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1967R

Anti-KLK9 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-1967R)
Dodavatel: Bioss
Popis: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1967R-CY5

Anti-KLK9 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-1967R-CY5)
Dodavatel: Bioss
Popis: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
Měrná jednotka: 1 * 100 µl
Image Unavailable-PROOBP619

Diclofenac sodium salt

Katalogové číslo: (PROOBP619)
Dodavatel: LGC Standards PROMOCHEM
Popis: Diclofenac sodium salt
Měrná jednotka: 1 * 100 mg
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