Hledali jste: 1-Phenyl-2-pyrimidin-4-ylethanone

Dodavatel: Apollo Scientific

Popis: MAPK/ERK Signalling Pathway

Katalogové číslo: (APOSBISN0043-1MG)

Dodavatel: Apollo Scientific

Popis: S63845 specifically binds with high affinity to the BH3-binding groove of MCL1. S63845 potently kills MCL1-dependent cancer cells, including multiple myeloma, leukaemia and lymphoma cells, by activating the BAX/BAK-dependent mitochondrial apoptotic pathway.

Měrná jednotka: 1 * 1 mg

Akce

Dodavatel: Apollo Scientific

Popis: IPI-549 is a selective phosphoinositide-3-kinase (PI3K)-γ inhibitor with IC50 of 16 nM as an immuno-oncology clinical candidate.

Dodavatel: ENZO LIFE SCIENCES

Popis: Inhibitor of PDK1, TBK1, IKK-ε, IRF3

New Product

Dodavatel: ENZO LIFE SCIENCES

Popis: Tyrosine kinase inhibitor.

New Product

Dodavatel: Apollo Scientific

Popis: Imatinib is the active ingredient in the drug sold under the trade name Gleevec® in USA or Glivec in Europe and Australia.

Dodavatel: ENZO LIFE SCIENCES

Popis: Potent and selective AMPK inhibitor.

New Product

Dodavatel: Apollo Scientific

Popis: Ethyl-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Dodavatel: Apollo Scientific

Popis: Phenyl(4,6-dimethoxypyrimidin-2-yl)carbamate

Dodavatel: Thermo Scientific

Popis: Imatinib mesylate 98%

Dodavatel: ENZO LIFE SCIENCES

Popis: Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

New Product

Katalogové číslo: (ACRO463250010)

Dodavatel: Thermo Scientific

Popis: Sildenafil citrate

Měrná jednotka: 1 * 1 g

Akce

Dodavatel: Apollo Scientific

Popis: 6-Phenylpyrimidine-2,4-diol

Dodavatel: Apollo Scientific

Popis: SCH772984 is a specific inhibitor of ERK12 with IC50 of 4 nM and 1 nM respectively.

Dodavatel: ENZO LIFE SCIENCES

Popis: Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.

New Product

Dodavatel: Apollo Scientific

Popis: Imatinib is the active ingredient in the drug sold under the trade name Gleevec® in USA or Glivec in Europe and Australia.