BX-795 ≥97% (by HPLC)
Dodavatel: ENZO LIFE SCIENCES
ENZCHM1890005
ENZCHM1890010
ENZOENZCHM1890005EA
2610
CZK
ENZOENZCHM1890005
ENZOENZCHM1890010
BX-795 ≥97% (by HPLC)
BX-795
Inhibitor of PDK1, TBK1, IKK-ε, IRF3
BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC50 = 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-ε. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC50 values ranging from submicromolar amounts (0.368 µM to greater than 450 µM).
Vzorec:
C₂₃H₂₆IN₇O₂S MW: 591,5 g/mol |
MDL Number:
MFCD12546134 CAS číslo: 702675-74-9 |
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