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Hledali jste: N-Stearoyl-D-erythro-sphingosine


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Image Unavailable-CAYM10009222-25

SKI-II ≥95%, crystalline solid

Dodavatel: Cayman Chemical
Popis: Sphingosine kinase isoforms, SPHK 1 and SPHK 2, catalyse the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 (SPHK I<sub>2</sub>) is a potent, selective inhibitor of SPHK 1 with anti-proliferative activity.

Image Unavailable-ENZOBMLPD1290050

EHNA ≥98% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Phosphodiesterase PDE II inhibitor, IC50=0.8 µM. Also inhibits adenosine deaminase, Ki=4 nM.

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Image Unavailable-ENZOBMLSL2330025

Fingolimod ≥98% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Novel immune modulator that alters migration and homing of lymphocytes. Acts as a potent agonist of sphingosine 1-phosphate receptors (S1P) after phosphorylation by sphingosine kinase. Also inhibits cytosolic phospholipase A2 independently of sphingosine 1-phosphate receptors.

New Product

Image Unavailable-BOSSBS-6021R

Anti-FOXD4 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-6021R)
Dodavatel: Bioss
Popis: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Měrná jednotka: 1 * 100 µl
Product Image-ACRO171660010

1,4-Dithioerythritol 99+%

Dodavatel: Thermo Fisher Scientific
Popis: 1,4-Dithioerythritol 99+%

Bezpečnostní list

Image Unavailable-SIAL171158-5G

Stearoyl chloride, Sigma-Aldrich®

Dodavatel: Merck
Popis: Stearoyl chloride, Sigma-Aldrich®

Product Image-ACRO461660010

L-Biopterin ≥98%

Dodavatel: Thermo Fisher Scientific
Popis: L-Biopterin ≥98%

Image Unavailable-SIAL85730-500ML

Stearoyl chloride, Sigma-Aldrich®

Dodavatel: Merck
Popis: Stearoyl chloride, Sigma-Aldrich®

Image Unavailable-A10138.03

1,4-Dithioerythritol ≥99%

Dodavatel: Thermo Fisher Scientific
Popis: 1,4-Dithioerythritol ≥99%

Bezpečnostní list Certifikáty

Image Unavailable-BOSSBS-2652R-A647

Anti-SPHK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-2652R-A647)
Dodavatel: Bioss
Popis: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2652R-CY5.5

Anti-SPHK1 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-2652R-CY5.5)
Dodavatel: Bioss
Popis: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2652R-CY5

Anti-SPHK1 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-2652R-CY5)
Dodavatel: Bioss
Popis: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2652R-FITC

Anti-SPHK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-2652R-FITC)
Dodavatel: Bioss
Popis: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Měrná jednotka: 1 * 100 µl
Image Unavailable-APOSBICL4314-25MG

Memantine lactose adduct 95%

Dodavatel: Apollo Scientific
Popis: Memantine lactose adduct 95%

Image Unavailable-BOSSBS-2652R-A488

Anti-SPHK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-2652R-A488)
Dodavatel: Bioss
Popis: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0136R-HRP

Anti-GCH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-0136R-HRP)
Dodavatel: Bioss
Popis: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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