Hledali jste: 4-Deoxy-4-fluoro-D-glucopyranose

Dodavatel: MP Biomedicals

Popis: D-(+)-Galactosamine hydrochloride is a powerful inhibitor of hepatic RNA synthesis.

Katalogové číslo: (PRSI91-989)

Dodavatel: ProSci Inc.

Popis: Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyses the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterised by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: MP Biomedicals

Popis: N-Acetyl-β-D-mannosamine hydrate is used as a substrate to identify, differentiate and characterise enzymes such as N-acetyl-glucosamine epimerase(s) and aldolase(s). N-Acetyl-D-mannosamine is used for the synthesis of of N-acetylneuraminic acid.

Katalogové číslo: (PRSI6305)

Dodavatel: ProSci Inc.

Popis: SPT2 Antibody: Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase. SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum. As in the case with SPT1, mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I), resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Spectrum Chemical

Popis: Sucralose, FCC is used as an artificial sweetener products that require a longer shelf life. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Katalogové číslo: (PRSI33-744)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-768)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce

Dodavatel: Thermo Fisher Scientific

Popis: 5-Fluoro-2'-deoxyuridine (floxuridine) 99+%

Bezpečnostní list

Dodavatel: Apollo Scientific

Popis: 3-Fluoro-4-iodobenzotrifluoride

Dodavatel: Apollo Scientific

Popis: 2-Fluoro-3-methoxybenzylamine

Dodavatel: Apollo Scientific

Popis: 2-Fluoro-5-nitroanisole

Dodavatel: Apollo Scientific

Popis: 3-Fluoro-4-methylpyridine

Dodavatel: Apollo Scientific

Popis: 2'-Fluoro-5'-nitroacetophenone

Katalogové číslo: (APOSPC300555-5G)

Dodavatel: Apollo Scientific

Popis: 2'-Fluoro-4'-nitroacetanilide

Měrná jednotka: 1 * 5 g

Akce

Dodavatel: Apollo Scientific

Popis: 2-Fluoro-5-methoxyaniline

Dodavatel: Apollo Scientific

Popis: 4-Fluoro-m-anisidine