Hledali jste: Boc-L-isoleucine

Dodavatel: Thermo Fisher Scientific

Popis: L(+)-Izoleucin cell culture reagent

Bezpečnostní list Certifikáty

Katalogové číslo: (PRSI56-721)

Dodavatel: ProSci Inc.

Popis: This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene.

Měrná jednotka: 1 * 400 µl

New Product Akce

Katalogové číslo: (PRSI29-925)

Dodavatel: ProSci Inc.

Popis: SLC16A8 is proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI30-795)

Dodavatel: ProSci Inc.

Popis: BCKDK belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. BCKDK is the key enzyme that regulates the activity state of the BCKD complex.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI25-901)

Dodavatel: ProSci Inc.

Popis: SLC16A6 is a proton-linked monocarboxylate transporter.It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (06846-50MG)

Dodavatel: Merck

Popis: Chlorimuron-ethyl is a member of sulfonylurea herbicides used wildly for pre- and post-emergence control of broad-leaved weeds in soybeans maize peanuts beans and other crops. It is characterised by very low application rates high herbicidal activity good crop selectivity and low toxicity. Chlorimuron-ethyl is an acetolactate synthase (ALS) inhibitor that acts by inhibiting the biosynthesis of the essential amino acids like valine leucine and isoleucine. This stops the plant growth as cell division of growing roots and shoots tips are inhibited.

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (PRSI90-257)

Dodavatel: ProSci Inc.

Popis: izTRAIL is a newly available, highly active recombinant form of soluble human TRAIL. Due to a trimerizing N-terminal isoleucine zipper (iz) motif the intrinsic trimerization of TRAIL, required for apoptosis-inducing activity of TRAIL, is enhanced when compared to non-tagged soluble human TRAIL (shTRAIL). Therefore, izTRAIL is a potent inducer of apoptosis in many human cancer cells, but not normal human hepatocytes. In addition, the half-life of izTRAIL is about eight-fold higher than the half-life of shTRAIL. These properties render izTRAIL highly suitable for both in vitro and in vivo use, particularly for studies in which investigators plan to transfer their in vitro results into an in vivo system with human cancer cells in xenotransplant settings examining susceptibility to TRAIL-induced apoptosis.

Měrná jednotka: 1 * 10 µG

Akce

Katalogové číslo: (PRSI92-387)

Dodavatel: ProSci Inc.

Popis: Methylmalonyl-CoA epimerase, mitochondrial（MCEE）is an enzyme which belongs to the glyoxalase I family. It converts (S)-methylmalonyl-CoA to the (R) form, catalyses the following chemical reaction: (R)-methylmalonyl-CoA (S)-methylmalonyl-CoA. It plays an important role in the catabolism of fatty acids with odd-length carbon chains. This protein deficiency is an autosomal recessive inborn error of AA metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria can appear in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI6215)

Dodavatel: ProSci Inc.

Popis: CTTNBL1 Antibody: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI31-325)

Dodavatel: ProSci Inc.

Popis: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: Apollo Scientific

Popis: N-Boc-glycine (boc-gly-OH) 97%

Dodavatel: Thermo Fisher Scientific

Popis: Boc-ON ≥98%

Bezpečnostní list Certifikáty

Dodavatel: Apollo Scientific

Popis: N-Boc-3-ethylpiperazine

Dodavatel: Apollo Scientific

Popis: (S)-1-Boc-2-azetidinemethanol

Dodavatel: Apollo Scientific

Popis: N-Boc-2-chloroethylamine

Dodavatel: Apollo Scientific

Popis: N-Boc-L-alanine