Hledali jste: (S)-(+)-Camptothecin

Dodavatel: Apollo Scientific

Popis: (S)-(+)-Camptothecin

Katalogové číslo: (API-02)

Dodavatel: G-Biosciences

Popis: Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).

Měrná jednotka: 1 * 1 mL

Akce

Dodavatel: ENZO LIFE SCIENCES

Popis: Potent antitumor agent

New Product

Dodavatel: Apollo Scientific

Popis: A potent antitumor antibiotic.

Dodavatel: Thermo Scientific

Popis: CAS No.: 7689-03-4

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Dodavatel: ENZO LIFE SCIENCES

Popis: Potent antitumor agent. Inhibitor of DNA-topoisomerase. Analog of (S)-(⁺)-camptothecin. Used in chemotherapy of several different cancers.

New Product

Dodavatel: Thermo Scientific

Popis: 7-Ethyl-10-hydroxycamptothecin 98%

Katalogové číslo: (API-16S)

Dodavatel: G-Biosciences

Popis: Apoptosis inducers are used for induction of apoptosis in cultured cells. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, doxorubicin and etoposide.

Měrná jednotka: 1 * 1 SET

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Dodavatel: Merck

Popis: Camptothecin is an alkaloid that exhibits anti-leukemic and anti-tumor activities.

Dodavatel: Cayman Chemical

Popis: SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC₅₀ = 8.8 nM) compared to irinotecan (IC₅₀ >100 nM).

Katalogové číslo: (ENZOBMLPI1100010)

Dodavatel: ENZO LIFE SCIENCES

Popis: A potent irreversible mechanism based serine protease inhibitor. Inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase and proteinase 3. Inhibits activation of neutral sphingomyelinase and apoptosis triggered by daunorubicin as well as camptothecin-induced apoptosis in HL-60 cells. Inhibits migration of eosinophils through basement membrane components in vitro.

Měrná jednotka: 1 * 10 mg

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Dodavatel: Apollo Scientific

Popis: Topotecan hydrochloride

Dodavatel: Thermo Scientific

Popis: Cytotoxic antitumor agent that inhibits topoisomerase I.

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Dodavatel: MP Biomedicals

Popis: (S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.

Dodavatel: Thermo Scientific

Popis: Topotecan hydrochloride hydrate 97%

New Product

Katalogové číslo: (BSBTPB9323)

Dodavatel: BosterBio

Popis: Polyclonal antibody for RAD51 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. RAD51 information: Molecular Weight: 36966 MW; Subcellular Localization: Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage. DNA damage induces an increase in nuclear levels. Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a SPIDR-dependent manner; Tissue Specificity: Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.

Měrná jednotka: 1 * 100 µG

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