7-Ethyl-10-hydroxycamptothecin ≥98%
Dodavatel: Cayman Chemical
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Nebezpečí
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15632-10
15632-50
15632-5
CAYM15632-10EA
3740
CZK
CAYM15632-10
CAYM15632-50
CAYM15632-5
7-Ethyl-10-hydroxycamptothecin ≥98%
7-Ethyl-10-hydroxycamptothecin
SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC50 = 8.8 nM) compared to irinotecan (IC50 >100 nM).
- SN-38 is in a form of crystalline solid
- λmax at 224, 267, 331, 368, 383 nm
Vzorec:
C₂₂H₂₀N₂O₅ Storage Temperature: Freezer |
MDL Number:
MFCD00871873 CAS číslo: 86639-52-3 UN: 2811 ADR: 6.1,III |
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