Hledali jste: Strychnine

Dodavatel: Thermo Fisher Scientific

Popis: Strychnine 98%

Bezpečnostní list

Dodavatel: Merck

Popis: Strychnine, Sigma-Aldrich®

Katalogové číslo: (EHERC16980000)

Dodavatel: EHRENSTORFER

Popis: Strychnine

Měrná jednotka: 1 * 0,25 g

Akce

Dodavatel: Merck

Popis: Strychnine hemisulphate, Sigma-Aldrich®

Katalogové číslo: (PRSI55-210)

Dodavatel: ProSci Inc.

Popis: Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium. GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP. Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.

Měrná jednotka: 1 * 400 µl

New Product Akce

Katalogové číslo: (ABCAAB120416-100)

Dodavatel: Abcam

Popis: STRYCHNINE HYDROCHLORIDE 1 * 100 mg

Měrná jednotka: 1 * 100 mg

Akce

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Katalogové číslo: (SIALPHL89801-100MG)

Dodavatel: Merck

Popis: STRYCHNINE 1 * 100 mg

Měrná jednotka: 1 * 100 mg

Akce

Katalogové číslo: (PROOLGCFOR0658.00)

Dodavatel: LGC Standards PROMOCHEM

Popis: STRYCHNINE NITRATE 1 * 10 mg

Měrná jednotka: 1 * 10 mg

Akce

Katalogové číslo: (PROOMM0658.02)

Dodavatel: LGC Standards PROMOCHEM

Popis: STRYCHNINE N-OXIDE HYDROCHLORIDE 1 * 100 mg

Měrná jednotka: 1 * 100 mg

Akce

Katalogové číslo: (SIALS8753-25G)

Dodavatel: Merck

Popis: STRYCHNINE HYDROCHLORIDE 1 * 25 g

Měrná jednotka: 1 * 25 g

Akce

Katalogové číslo: (PROOMM0658.00)

Dodavatel: LGC Standards PROMOCHEM

Popis: STRYCHNINE NITRATE 1 * 500 mg

Měrná jednotka: 1 * 500 mg

Akce

Katalogové číslo: (55513-100MG)

Dodavatel: Merck

Popis: Organic Standard, Spermine, ≥99,0% (GC), 97,0 - 103,0% (T)

Měrná jednotka: 1 * 100 mg

Akce

Dodavatel: MP Biomedicals

Popis: Hypotaurine is a Non-specific, endogenous inhibitory glycine receptor agonist.

Katalogové číslo: (ANTIA83535-100)

Dodavatel: ANTIBODIES.COM

Popis: Goat polyclonal antibody to alpha 1 Glycine Receptor for ELISA, WB and IHC with samples derived from human, mouse and rat.

Měrná jednotka: 1 * 100 µG

New Product Akce

Dodavatel: MP Biomedicals

Popis: Spermine is a naturally occuring polyamine that occurs in all eukaryotes, but is rare in prokaryotes. It is essential for cell growth in both normal and neoplastic tissue.

Dodavatel: MP Biomedicals

Popis: Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.