Hledali jste: Stearoyl+chloride

9 810 výsledků nalezeno

Upřesnit hledání Třídit podle

Sort Results

Zobrazit seznam Rychlý náhled (novinka)

Porovnat(0) Smazat

Ohodnoťte výsledky hledání

Anti-SCD1 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI36-230)

Dodavatel: ProSci Inc.

Popis: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

Měrná jednotka: 1 * 100 µG

Akce

N/A Each

Anti-SCD5 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI56-815)

Dodavatel: ProSci Inc.

Popis: Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).

Měrná jednotka: 1 * 400 µl

New Product Akce

N/A Each

Anti-ELOVL6 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI4571)

Dodavatel: ProSci Inc.

Popis: ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Měrná jednotka: 1 * 100 µG

Akce