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Image Unavailable-BOSSBS-10235R-A750

Anti-Pokemon/ZBTB7 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-10235R-A750)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumourigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10235R-CY5

Anti-ZBTB7 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-10235R-CY5)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10235R-A680

Anti-Pokemon/ZBTB7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-10235R-A680)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumourigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10235R-HRP

Anti-ZBTB7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-10235R-HRP)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Product Image-3836-07

Fosforečnan sodný dodekahydrát 98.0-102.0% (by acidimetry), crystals, BAKER ANALYZED® ACS, J.T.Baker®

Katalogové číslo: (3836-07)
Dodavatel: Avantor
Popis: Crystals. Lot analysis on label.
Měrná jednotka: 1 * 12 kg

Certifikáty


Product Image-7940-20

Fosforečnan sodný dodekahydrát 98.0-102.0%, crystals, AR® ACS, Macron Fine Chemicals™

Dodavatel: Avantor
Popis: Fosforečnan sodný dodekahydrát 98.0-102.0%, crystals, AR® ACS, Macron Fine Chemicals™

Image Unavailable-BOSSBS-10235R-A488

Anti-ZBTB7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-10235R-A488)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10235R-CY3

Anti-ZBTB7 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-10235R-CY3)
Dodavatel: Bioss
Popis: Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
Měrná jednotka: 1 * 100 µl
Image Unavailable-0307.1000

Fosforečnan sodný dodekahydrát, BAKER ANALYZED® ACS, J.T.Baker®

Katalogové číslo: (0307.1000)
Dodavatel: Avantor
Popis: Fosforečnan sodný dodekahydrát, BAKER ANALYZED® ACS, J.T.Baker®
Měrná jednotka: 1 * 1 kg

Certifikáty


Product Image-ACRO446222500

Dihydrogenfosforečnan sodný dihydrát for HPLC

Katalogové číslo: (ACRO446222500)
Dodavatel: Thermo Fisher Scientific
Popis: Dihydrogenfosforečnan sodný dihydrát for HPLC
Měrná jednotka: 1 * 250 g

Certifikáty


Product Image-85742.290

Fosforečnan sodný dodekahydrát 98.0-102.0%, AnalaR NORMAPUR® Reag. Ph.Eur., ACS

Dodavatel: VWR Chemicals
Popis: Fosforečnan sodný dodekahydrát 98.0-102.0%, AnalaR NORMAPUR® Reag. Ph.Eur., ACS

Bezpečnostní list Certifikáty

Product Image-ACRO447760250

Dihydrogenfosforečnan sodný dihydrát 98%, extra pure

Dodavatel: Thermo Fisher Scientific
Popis: Dihydrogenfosforečnan sodný dihydrát 98%, Extra Pure

Bezpečnostní list

Image Unavailable-11591.30

Dihydrogenfosforečnan sodný monohydrát 98.0-102.0% ACS

Dodavatel: Thermo Fisher Scientific
Popis: Dihydrogenfosforečnan sodný monohydrát 98.0-102.0% ACS

Bezpečnostní list Certifikáty

Image Unavailable-10870.14

Dihydrogenfosforečnan sodný monohydrát ≥99.998% (metals basis), Puratronic®

Dodavatel: Thermo Fisher Scientific
Popis: Dihydrogenfosforečnan sodný monohydrát ≥99.998% (metals basis), Puratronic®

Bezpečnostní list Certifikáty

Image Unavailable-A15713.36

Fosforečnan sodný dodekahydrát ≥97%

Dodavatel: Thermo Fisher Scientific
Popis: Fosforečnan sodný dodekahydrát ≥97%

Bezpečnostní list Certifikáty

Image Unavailable-BOSSBS-11304R

Anti-RFC1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-11304R)
Dodavatel: Bioss
Popis: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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