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Product Image-PRSI28-705

Anti-POU2F1 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI28-705)
Dodavatel: ProSci Inc.
Popis: POU2F1 is a member of the POU family that represents the double-stranded DNA binding proteins specifically binding to the block C region.
Měrná jednotka: 1 * 100 µG
Image Unavailable-BOSSBS-8867R-A488

Anti-GHRHR Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-8867R-A488)
Dodavatel: Bioss
Popis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11794R-A350

Anti-GHRHR Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-11794R-A350)
Dodavatel: Bioss
Popis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Měrná jednotka: 1 * 100 µl
Product Image-PRSI27-318

Anti-POU3F2 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI27-318)
Dodavatel: ProSci Inc.
Popis: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Měrná jednotka: 1 * 50 µG
Product Image-PRSI31-236

Anti-POU5F1 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI31-236)
Dodavatel: ProSci Inc.
Popis: POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm
Měrná jednotka: 1 * 100 µG
Product Image-BSBTPA1506

Anti-BOB1 Rabbit Polyclonal Antibody

Katalogové číslo: (BSBTPA1506)
Dodavatel: Boster Bio
Popis: Rabbit IgG polyclonal antibody for POU domain class 2-associating factor 1(POU2AF1) detection. Tested with WB, IHC-P in Mouse; Rat.
Měrná jednotka: 1 * 0,1 mg
Product Image-PRSI55-446

Anti-POU5F1B Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI55-446)
Dodavatel: ProSci Inc.
Popis: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
Měrná jednotka: 1 * 400 µl

New Product


Product Image-PRSI27-625

Anti-POU2F3 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI27-625)
Dodavatel: ProSci Inc.
Popis: POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes.
Měrná jednotka: 1 * 50 µG
Product Image-PRSI28-073

Anti-POU2F2 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI28-073)
Dodavatel: ProSci Inc.
Popis: POU2F2 is a member of the POU family and is predominantly expressed in B cells, in activated T cells, and in the nervous system.
Měrná jednotka: 1 * 100 µG
Product Image-PRSI31-205

Anti-POU3F2 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI31-205)
Dodavatel: ProSci Inc.
Popis: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Měrná jednotka: 1 * 50 µG
Image Unavailable-PRSI77-024

Anti-POU5F1; Pou5f1 Rat Monoclonal Antibody [clone: EM92] (PE (Phycoerythrin))

Katalogové číslo: (PRSI77-024)
Dodavatel: ProSci Inc.
Popis: The EM92 monoclonal antibody reacts with human and mouse Oct 3/4, a POU family transcription factor. Oct 3/4 is encoded by the Pou5F1 gene and expressed on undifferentiated cells and lost in adult tissue. Fbx15, FGF-4, NANOG, Rex1, and UTF1 expression is regulated with Oct 3/4 and in many cases gene expression is regulated in concert with Sox2.
Měrná jednotka: 1 * 0,1 mg

New Product


Image Unavailable-USBI145557

Anti-Oct-4A Mouse Monoclonal Antibody NL®)493 [clone: 653108]

Katalogové číslo: (USBI145557)
Dodavatel: US Biological
Popis: Anti-Oct-4A Mouse Monoclonal Antibody NL®)493 [clone: 653108]
Měrná jednotka: 1 * 500 µl
Image Unavailable-USBI145558

Anti-Oct-4A Mouse Monoclonal Antibody NL®)557 [clone: 653108]

Katalogové číslo: (USBI145558)
Dodavatel: US Biological
Popis: Anti-Oct-4A Mouse Monoclonal Antibody NL®)557 [clone: 653108]
Měrná jednotka: 1 * 500 µl
Image Unavailable-PRSI33-464

Anti-SOX10 Mouse Monoclonal Antibody [clone: SPM607]

Katalogové číslo: (PRSI33-464)
Dodavatel: ProSci Inc.
Popis: Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia (By similarity). [UniProt].
Měrná jednotka: 1 * 100 µG

New Product


Image Unavailable-PRSI77-025

Anti-POU5F1; Pou5f1 Rat Monoclonal Antibody [clone: EM92] (PE (Phycoerythrin))

Katalogové číslo: (PRSI77-025)
Dodavatel: ProSci Inc.
Popis: The EM92 monoclonal antibody reacts with human and mouse Oct 3/4, a POU family transcription factor. Oct 3/4 is encoded by the Pou5F1 gene and expressed on undifferentiated cells and lost in adult tissue. Fbx15, FGF-4, NANOG, Rex1, and UTF1 expression is regulated with Oct 3/4 and in many cases gene expression is regulated in concert with Sox2.
Měrná jednotka: 1 * 0,025 mg

New Product


Product Image-PRSI7085

Anti-POU3F2 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI7085)
Dodavatel: ProSci Inc.
Popis: POU3F2 Antibody: POU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage. Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases.
Měrná jednotka: 1 * 100 µG
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
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Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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