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Anti-CECR6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-9006R-A647)

Dodavatel: Bioss

Popis: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-CECR6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-9006R-A350)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Accessories for heating and drying ovens, Universal UN/UNplus and UF/UFplus

Dodavatel: MEMMERT

Popis: Accessories for heating and drying ovens, Universal UN/UNplus and UF/UFplus

Tubes and systems for active sampling

Dodavatel: Dräger

Popis: Sampling activated tubes for direct measurement indication even with complex compounds and mixtures of substances in air investigations and gas analyses.

Factory fitted options for Memmert UNpa series Paraffin ovens

Dodavatel: MEMMERT

Popis: Factory fitted options for Memmert UNpa series Paraffin ovens

Anti-SHH Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI29-969)

Dodavatel: ProSci Inc.

Popis: SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.This gene, which is expressed only during embryogenesis, encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.

Měrná jednotka: 1 * 50 µG

Akce

N/A Each

VWR® ELSD LC, ELSD FP, ELSD 100, Low Temperature Evaporative Light-Scattering Detectors

Dodavatel: VWR Collection

Popis: Tyto ELSD modely kombinují jednoduchost, spolehlivost a odolnost pro všechny analýzy nebo purifikace. Umožňují detekci všech zásadních složek. Detekce je založena na univerzálních vlastnostech všech analytů a nevyžaduje přítomnost chromoforů ani elektroaktivních skupin atd. Systém může být ovládán manuálně nebo prostřednictvím PC. Pro minimalizace nákladů a prodloužení doby životnosti je možné nastavit režim vzdáleného vypnutí.