Hledali jste: Chloroform-D1

Katalogové číslo: (BOSSBS-9015R-A680)

Dodavatel: Bioss

Popis: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Biorbyt

Popis: Human VEGF receptor 1 D1-3 (from Insect cells)

Katalogové číslo: (BOSSBS-10319R-FITC)

Dodavatel: Bioss

Popis: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0559R)

Dodavatel: Bioss

Popis: CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (1.13363.0010)

Dodavatel: Merck

Popis: Trifluoroacetic acid-[D₁] (99.5% D) for NMR spectroscopy, Sigma-Aldrich®

Měrná jednotka: 1 * 10 mL

Bezpečnostní list Akce

Katalogové číslo: (BOSSBS-6000R-A350)

Dodavatel: Bioss

Popis: DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene. (from Entrez gene). DACH1 has also been found to inhibit oncogene-mediated breast tumor growth via downregulation of cyclin D1. Expression of DACH1 has been found to inversely correlate with metastasis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (PRSI24-257)

Dodavatel: ProSci Inc.

Popis: Anti-Flavivirus Group Antigen Recombinant Antibody [Clone: D1-4G2-4-15 (4G2)]

Měrná jednotka: 1 * 0,2 mg

New Product Akce

Katalogové číslo: (BIRBORB108893-100)

Dodavatel: Biorbyt

Popis: Anti-G 5-D1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µG

Akce

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Katalogové číslo: (BOSSBS-5963R-A647)

Dodavatel: Bioss

Popis: CDCA7L is a member of the CDCA (cell division cycle associated) protein family. Members of this family have expression patterns associated with other known cell cycle genes such as cyclins and CDC genes. CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It is involved in apoptotic signaling pathways and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Merck

Popis: Bromoform-[D₁], Sigma-Aldrich®

Katalogové číslo: (BOSSBS-11260R-FITC)

Dodavatel: Bioss

Popis: Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11260R-HRP)

Dodavatel: Bioss

Popis: Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Merck

Popis: Ethanol-[D₁], Sigma-Aldrich®

Katalogové číslo: (SIAL488682-5L)

Dodavatel: Merck

Popis: Deuterium chloride, Sigma-Aldrich®

Měrná jednotka: 1 * 5 L

Akce

Katalogové číslo: (BOSSBS-9015R-CY7)

Dodavatel: Bioss

Popis: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9015R-A350)

Dodavatel: Bioss

Popis: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.

Měrná jednotka: 1 * 100 µl

Akce