Hledali jste: Chloroform-D1

Dodavatel: Thermo Fisher Scientific

Popis: Phenol:Chloroform:Isoamyl alcohol 25:24:1 is used in the extraction of DNA for the generation of DNA minisatellite fingerprints. It is also used for purifying RNA.

Bezpečnostní list Certifikáty

Katalogové číslo: (ANTIA11552-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to Cyclin D1 for WB with samples derived from human, mouse and rat.

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (ORIGCF505225)

Dodavatel: OriGene

Popis: Anti-PIK3CG Mouse Monoclonal Antibody [clone: D1]

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (ABNOH00003155-M01)

Dodavatel: Abnova

Popis: Anti-HMGCL Mouse Monoclonal Antibody [clone: 4F4-D1]

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BOSSBS-11260R-A647)

Dodavatel: Bioss

Popis: Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9015R-A680)

Dodavatel: Bioss

Popis: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-10319R-FITC)

Dodavatel: Bioss

Popis: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5228R)

Dodavatel: Bioss

Popis: Cell cycle progression is regulated by cyclins and their cognate Cdks. p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. p27 Kip1 is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27 Kip 1; while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0559R)

Dodavatel: Bioss

Popis: CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (EHERL17739500ME)

Dodavatel: EHRENSTORFER

Popis: Organic Standard, Chloroform 10 µg/ml v methanolu, Typ balení: Glass bottle

Měrná jednotka: 1 * 10 mL

Akce

Katalogové číslo: (SIAL488682-5L)

Dodavatel: Merck

Popis: Deuterium chloride, Sigma-Aldrich®

Měrná jednotka: 1 * 5 L

Akce

Dodavatel: Merck

Popis: Ethanol-[D₁], Sigma-Aldrich®

Katalogové číslo: (ABNOMAB15450)

Dodavatel: Abnova

Popis: Mouse monoclonal antibody raised against native mouse H2-D1.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: MP Biomedicals

Popis: Practically insoluble in water. Miscible with ethanol, acetone, chloroform, ether.

Katalogové číslo: (ANTIA253039-100)

Dodavatel: ANTIBODIES.COM

Popis: Mouse monoclonal [CCND1/2593] antibody to Cyclin D1 for IHC-P with samples derived from Human.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (ANTIA249859-100)

Dodavatel: ANTIBODIES.COM

Popis: Mouse monoclonal [CCND1/2593] antibody to Cyclin D1 for IHC-P with samples derived from human.

Měrná jednotka: 1 * 100 µG

New Product Akce