Hledali jste: 5-Fluorouridine

Dodavatel: Apollo Scientific

Popis: 5-Fluorouridine 97%

Dodavatel: Apollo Scientific

Popis: 2'-Deoxy-2'-fluorouridine 98%

Dodavatel: Thermo Scientific

Popis: 5-Fluoro-5'-deoxyuridine (Doxifluridine)

Dodavatel: Thermo Scientific

Popis: 2'-Deoxy-2'-fluorouridine 97%

Bezpečnostní list

Katalogové číslo: (APOSBIMN2019-1G)

Dodavatel: Apollo Scientific

Popis: 2’-Deoxy-2’-fluorouridine-3’-CE-phosphoramidite ≥95%

Měrná jednotka: 1 * 1 g

Akce

Dodavatel: Apollo Scientific

Popis: (+)-5-Fluoro-5'-deoxyuridine

Dodavatel: Thermo Scientific

Popis: 5-Fluorouridine ≥97%

Bezpečnostní list Certifikáty

Dodavatel: Thermo Scientific

Popis: 2'-Deoxy-2'-fluorouridine 97%

Bezpečnostní list Certifikáty

Dodavatel: Merck

Popis: 5-Fluorouridine, Sigma-Aldrich®

Katalogové číslo: (J64217.06)

Dodavatel: Thermo Scientific

Popis: 5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyuridine 98%

Měrná jednotka: 1 * 5 g

Bezpečnostní list Certifikáty Akce

Katalogové číslo: (PRSI55-545)

Dodavatel: ProSci Inc.

Popis: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

Měrná jednotka: 1 * 400 µl

New Product Akce

Katalogové číslo: (PRSIXW-8050)

Dodavatel: ProSci Inc.

Popis: FUNCTION: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: Merck

Popis: 5-Fluoro-5'-deoxyuridine (Doxifluridine), Sigma-Aldrich®

Katalogové číslo: (PRSI33-744)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-768)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PHR2850-50MG)

Dodavatel: Merck

Popis: [EN]5-DEOXY-5-FLUOROURIDINE 1 * 50 mg

Měrná jednotka: 1 * 50 mg

Akce