Hledali jste: 5-Aza-2\'-deoxycytidine

Dodavatel: Apollo Scientific

Popis: 5-Aza-2'-deoxycytidine free base

Katalogové číslo: (ENZOALX480096M005)

Dodavatel: ENZO LIFE SCIENCES

Popis: DNA methyltransferase inhibitor

Měrná jednotka: 1 * 5 mg

New Product Akce

Dodavatel: Thermo Scientific

Popis: Appearance: White to off-white Powder

Bezpečnostní list

Katalogové číslo: (BOSSBS-6548R)

Dodavatel: Bioss

Popis: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: MP Biomedicals

Popis: 5-Aza-2'-deoxycytidine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling "opening" chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.

Katalogové číslo: (PRSI5667)

Dodavatel: ProSci Inc.

Popis: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI5499)

Dodavatel: ProSci Inc.

Popis: MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI91-734)

Dodavatel: ProSci Inc.

Popis: Proline-rich acidic protein 1, also known as Uterine-specific proline-rich acidic protein, UPA and PRAP1, is a secreted protein. PRAP1 is abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. PRAP1 is up-regulated by butyrate, trichostatin A and 5'-aza-2' deoxycytidine. PRAP1 may play an important role in maintaining normal growth homeostasis in epithelial cells. PRAP1 is suppressed through epigenetic mechanisms involving histone deacetylation and methylation. PRAP1 has been shown to cause cell growth inhibition in cancer cell lines.

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: Apollo Scientific

Popis: 2'-Deoxycytidine

Dodavatel: Thermo Scientific

Popis: 2'-Deoxycytidine 99+%

Bezpečnostní list

Dodavatel: Thermo Scientific

Popis: 2'-Deoxycytidine hydrochloride 98%

Dodavatel: Thermo Scientific

Popis: N4-Benzoyl-2'-deoxycytidine ≥98%

Bezpečnostní list Certifikáty

Dodavatel: Thermo Scientific

Popis: 2'-Deoxycytidine hydrochloride ≥99%

Bezpečnostní list Certifikáty

Katalogové číslo: (40036.)

Dodavatel: Biotium

Popis: Biotin-11-dCTP (Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt) can be enzymatically incorporated into DNA via nick translation, random priming, or 3′-end terminal labeling. The number 11 is the number of atoms in the linker between biotin and dCTP.

Měrná jednotka: 1 * 50 µl

Akce

Katalogové číslo: (H52303.06)

Dodavatel: Thermo Scientific

Popis: Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.

Měrná jednotka: 1 * 5 g

Bezpečnostní list Certifikáty Akce

Katalogové číslo: (APOSOR40355-1G)

Dodavatel: Apollo Scientific

Popis: 2'-Deoxy-5-methylcytidine

Měrná jednotka: 1 * 1 g

Akce