Hledali jste: 5(6)-Carboxy-2\',7\'-dichlorofluorescein+(CDCF)

Katalogové číslo: (BOSSBS-11987R-A680)

Dodavatel: Bioss

Popis: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11987R-HRP)

Dodavatel: Bioss

Popis: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (90008.)

Dodavatel: Biotium

Popis: Free acid form of 6-TAMRA (6-carboxytetramethylrhodamine) single isomer. 6-Carboxytetramethylrhodamine, triethylammonium salt is a single isomer rhodamine dye. The 6-carboxy group can be activated to succinimidyl ester or mixed anhydride for coupling with amines using standard methods.

Měrná jednotka: 1 * 10 mg

Akce

Dodavatel: Apollo Scientific

Popis: Mycophenolic acid-O-β-D-glucuronide ≥97%

Katalogové číslo: (APOSOR110753-500MG)

Dodavatel: Apollo Scientific

Popis: 3,4-Dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxylic acid

Měrná jednotka: 1 * 500 mg

Akce

Katalogové číslo: (ENZOADICSA614E)

Dodavatel: ENZO LIFE SCIENCES

Popis: The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BOSSBS-11987R-CY7)

Dodavatel: Bioss

Popis: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Thermo Fisher Scientific

Popis: 5-Fluoroindole-2-carboxylic acid ≥98%

Bezpečnostní list Certifikáty

Katalogové číslo: (BOSSBS-11987R-A647)

Dodavatel: Bioss

Popis: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (APOSOR2441-250MG)

Dodavatel: Apollo Scientific

Popis: 1-(3-Aminoprop-1-yl)-5-(tert-butyl)-2-methyl-1H-pyrrole-3-carboxylic acid, 1-BOC protected

Měrná jednotka: 1 * 250 mg

Akce

Katalogové číslo: (USBIC4125-03L)

Dodavatel: US Biological

Popis: Anti-STUB1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (APOSOR12220-250MG)

Dodavatel: Apollo Scientific

Popis: 3,4-Dihydro-4-methyl-2H-pyrido[3,2-b][1,4]oxazine-7-carboxylic acid 95+%

Měrná jednotka: 1 * 250 mg

Akce

Dodavatel: Thermo Fisher Scientific

Popis: 5-Fluoroindole-2-carboxylic acid 98%

Bezpečnostní list

Katalogové číslo: (USBIC7947-98C)

Dodavatel: US Biological

Popis: Anti-CTDSP1 Goat polyclonal antibody

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Apollo Scientific

Popis: 4-(Trifluoromethyl)anthranilic acid 98%

Katalogové číslo: (AATB21228)

Dodavatel: AAT BIOQUEST

Popis: 5-(and-6)-Carboxy SNARF-1 Maleimide is an excellent thiol-reactive building block that can be used for developing SNARF-1 pH probes.

Měrná jednotka: 1 * 1 mg

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