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Popis: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Katalogové číslo: BNCB1010-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Katalogové číslo: BNC471010-500
Měrná jednotka: 1 * 500 µl
Dodavatel: Biotium


Popis: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Katalogové číslo: BNC681010-500
Měrná jednotka: 1 * 500 µl
Dodavatel: Biotium


Popis: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Katalogové číslo: BNC941010-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: Zlato ≥99.99% (metals basis), wire, Premion®, Ø 0.127 mm (0.005 in)
Katalogové číslo: 00130.G2
Měrná jednotka: 1 * 2 m
Dodavatel: Thermo Fisher Scientific

Popis: Vanad ≥99.8% (metals basis), foil, Thickness: 0.127 mm (0.005 in)
Katalogové číslo: 13783.FY
Měrná jednotka: 1 * 1 KS
Dodavatel: Thermo Fisher Scientific

Popis: cín ≥99.999% (metals basis), foil, Thickness: 0.127 mm (0.005 in)
Katalogové číslo: 00344.GE
Měrná jednotka: 1 * 1 KS
Dodavatel: Thermo Fisher Scientific

Popis: HRP Rabbit monoclonal [E132] to JAK1 (phospho Y1034 + Y1035) + JAK2 (phospho Y1007 + Y1008).
Katalogové číslo: ABCAAB303046-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Sodnovápenaté sklo.
Katalogové číslo: VTRA2520-04S
Měrná jednotka: 1 * 1 KS
Dodavatel: VTR Glass


Popis: Rabbit monoclonal [EP2310AY] to Filamin A (phospho S2152) + Filamin B (phospho S2107) - BSA and Azide free.
Katalogové číslo: ABCAAB284727-1
Měrná jednotka: 1 * 1 mg
Dodavatel: Abcam


Popis: thiosíran sodný pentahydrát 99.5-101.0% ACS
Katalogové číslo: 14518.A3
Měrná jednotka: 1 * 2 kg
Dodavatel: Thermo Fisher Scientific

Popis: AR-Glas®.
Katalogové číslo: 613-2111
Měrná jednotka: 1 * 1 KS
Dodavatel: HIRSCHMANN


Popis: Sodnovápenaté sklo.
Katalogové číslo: VTRA2500-18
Měrná jednotka: 1 * 1 KS
Dodavatel: TECHNOSKLO


Popis: Hliník ≥99.9995% (metals basis), foil, Puratronic®, Thickness: 0.038 +/- 0.007 mm (0.0015 +/- 0.0003 in)
Katalogové číslo: 38366.HC
Měrná jednotka: 1 * 1 KS
Dodavatel: Thermo Fisher Scientific

Popis: Zlato ≥99.9% (metals basis), thin foil, Thickness: 0.007 mm (0.00028 in)
Katalogové číslo: 44139.FF
Měrná jednotka: 1 * 1 KS
Dodavatel: Thermo Fisher Scientific

Popis: Protect your light-sensitive samples.
Katalogové číslo: MFLX95809-28
Měrná jednotka: 1 * 100 Feet
Dodavatel: Avantor Fluid Handling