Hledali jste: N-Hexanoyl-D-erythro-sphingosine

Dodavatel: Apollo Scientific

Popis: A biologically active, cell permeable, nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10nM & activiates MAP kinase.

Dodavatel: ENZO LIFE SCIENCES

Popis: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

New Product

Dodavatel: Cayman Chemical

Popis: C6 NBD-Ceramide (d18:1/6:0)

Katalogové číslo: (60030.)

Dodavatel: Biotium

Popis: NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.

Měrná jednotka: 1 * 1 mg

Akce

Dodavatel: Cayman Chemical

Popis: D-erythro-Sphingosine C-17 is a naturally-occurring but uncommon form of sphingosine, accounting for approximately 13% of the sphingosine in human skin.

Dodavatel: Thermo Scientific

Popis: Appearance: White to cream Powder or waxy solid

Bezpečnostní list

Katalogové číslo: (ENZOBMLEI1550100)

Dodavatel: ENZO LIFE SCIENCES

Popis: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

Měrná jednotka: 1 * 100 mg

New Product Akce

Katalogové číslo: (ENZOALX306017C500)

Dodavatel: ENZO LIFE SCIENCES

Popis: D-erythro-Sphingosine-1-phosphate (caged) ≥95%

Měrná jednotka: 1 * 500 µG

New Product Akce

Dodavatel: Cayman Chemical

Popis: C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.

Dodavatel: Thermo Scientific

Popis: D-erythro-Sphingosine hydrochloride 97%

Bezpečnostní list Certifikáty

Katalogové číslo: (ENZOALX306011M025)

Dodavatel: ENZO LIFE SCIENCES

Popis: PKC inhibitor

Měrná jednotka: 1 * 25 mg

New Product Akce

Dodavatel: ENZO LIFE SCIENCES

Popis: Sphingosine kinase inhibitor

New Product

Dodavatel: ENZO LIFE SCIENCES

Popis: Sphingosine precursor

New Product

Katalogové číslo: (BOSSBS-2653R-CY5.5)

Dodavatel: Bioss

Popis: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2653R-A647)

Dodavatel: Bioss

Popis: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2653R-A488)

Dodavatel: Bioss

Popis: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.

Měrná jednotka: 1 * 100 µl

Akce