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N-Acetylneuraminic acid methyl ester 97% min

Dodavatel: Apollo Scientific
Popis: N-Acetylneuraminic acid methyl ester 97% min

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Human recombinant sialate O-Acetylesterase (from cells)

Katalogové číslo: (PRSI91-729)
Dodavatel: ProSci Inc.
Popis: Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. SIAE is widely expressed with high expression levels in the testis, prostate, and colon. SIAE catalyses N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate. SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for immunological tolerance. Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.
Měrná jednotka: 1 * 50 µG

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N-Acetylneuraminic acid 97%

Dodavatel: Apollo Scientific
Popis: N-Acetylneuraminic acid 97%

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N-Acetylneuraminic acid 98%

Dodavatel: Apollo Scientific
Popis: N-Acetylneuraminic acid 98%

Image Unavailable-APOSOR8230T-5MG

5-Bromo-4-chloro-3-indolyl-α-D-N-acetylneuraminic acid

Katalogové číslo: (APOSOR8230T-5MG)
Dodavatel: Apollo Scientific
Popis: A substrate for the detection of sialidase-like enzyme,screening of enzymes, studying the physiological role of gangliosides, & for recombinant technologies.
Měrná jednotka: 1 * 5 mg
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N-Acetylneuraminic acid 97%

Dodavatel: Thermo Scientific
Popis: N-Acetylneuraminic acid 97%

Bezpečnostní list Certifikáty

Product Image-ACRO227040250

N-Acetylneuraminic acid 99%

Dodavatel: Thermo Scientific
Popis: Appearance: White to off-white Powder

Bezpečnostní list

Product Image-ENZOALX305010M250

N-Acetylneuraminic acid ≥97% (by HPLC)

Katalogové číslo: (ENZOALX305010M250)
Dodavatel: ENZO LIFE SCIENCES
Popis: N-Acetylneuraminic acid ≥97% (by HPLC)
Měrná jednotka: 1 * 250 mg

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2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

Dodavatel: Apollo Scientific
Popis: 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

Image Unavailable-APOSBICS0105-10MG

5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt

Dodavatel: Apollo Scientific
Popis: 5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt

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N-Acetylneuraminic Acid, Reference Standard

Katalogové číslo: (1612619.)
Dodavatel: USP
Popis: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
Měrná jednotka: 1 * 200 mg
Image Unavailable-BOSSBS-9882R-A680

Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-9882R-A680)
Dodavatel: Bioss
Popis: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumourigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterised by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterised by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9882R-A750

Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-9882R-A750)
Dodavatel: Bioss
Popis: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumourigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterised by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterised by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
Měrná jednotka: 1 * 100 µl
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Anti-RBC Rabbit Polyclonal Antibody

Katalogové číslo: (ROCK113-4139)
Dodavatel: Rockland Immunochemicals
Popis: Anti-Sheep Red Blood Cell Antibody may be used in hemagglutination assays. Haemagglutination assay or HA is a method of quantification for viruses or bacteria by hemagglutination. Some viral families and many bacteria have envelope or surface proteins which are able to agglutinate (stick to) human or animal red blood cells (RBC) and bind to N-acetylneuraminic acid. As each of the agglutinating molecule attaches to multiple RBCs, a lattice-structure will form. Normally, a virus dilution (e.g. 2-fold from 1:4 to 1:4096) will be applied to an RBC dilution (e.g. 0.1% to 0.7% in steps of 0.2%) for approx. 30 min, often at 4° C, otherwise viruses with neuraminidase activity will detach the virus from the RBCs. Then the lattice forming parts will be counted and the titer calculated. The titer of a hemagglutination assay is determined by the last viable "lattice" structure found. This is because it is at the point where, if diluted anymore, the amount of Virus particles will be less than that of the RBCs and thus not be able to agglutinate them together. Anti-SHEEP Red Blood Cell Antibody is used to sensitize erythrocytes and quantitate agglutination.
Měrná jednotka: 1 * 2 mL
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Anti-RBC Rabbit Polyclonal Antibody

Katalogové číslo: (ROCK103-4139)
Dodavatel: Rockland Immunochemicals
Popis: Anti-Chicken Red Blood Cell Antibody may be used in hemagglutination assays. Haemagglutination assay or HA is a method of quantification for viruses or bacteria by hemagglutination. Some viral families and many bacteria have envelope or surface proteins which are able to agglutinate (stick to) human or animal red blood cells (RBC) and bind to N-acetylneuraminic acid. As each of the agglutinating molecule attaches to multiple RBCs, a lattice-structure will form. Normally, a virus dilution (e.g. 2-fold from 1:4 to 1:4096) will be applied to an RBC dilution (e.g. 0.1% to 0.7% in steps of 0.2%) for approx. 30 min, often at 4° C, otherwise viruses with neuraminidase activity will detach the virus from the RBCs. Then the lattice forming parts will be counted and the titer calculated. The titer of a hemagglutination assay is determined by the last viable "lattice" structure found. This is because it is at the point where, if diluted anymore, the amount of Virus particles will be less than that of the RBCs and thus not be able to agglutinate them together. Anti-CHICKEN Red Blood Cell Antibody is used to sensitize erythrocytes and quantitate agglutination.
Měrná jednotka: 1 * 2 mL
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N-Acetylneuraminic acid ≥98%, powder

Dodavatel: MP Biomedicals
Popis: Soluble in water.

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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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