Hledali jste: Malonyl+coenzyme+A+lithium+salt

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Malonyl coenzyme A lithium salt ≥90%

Dodavatel: Cayman Chemical

Popis: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Dodavatel: Merck

Popis: Organic Standard, Malonyl-ʟ-carnitine lithium salt

Cerulenin ≥98%, crystalline solid

Dodavatel: Cayman Chemical

Popis: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-12952R-A680)

Dodavatel: Bioss

Popis: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-12954R-A680)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Katalogové číslo: (BOSSBS-12954R-A750)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-12952R-A750)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Coenzyme A trilithium salt

Dodavatel: Apollo Scientific

Popis: Coenzyme A trilithium salt

4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Dodavatel: Cayman Chemical

Popis: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Coenzyme A sodium salt hydrate ≥95%

Dodavatel: Cayman Chemical

Popis: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

Riboflavin 5'-monophosphate sodium salt hydrate

Dodavatel: Cayman Chemical

Popis: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

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