Hledali jste: Lázn\u011B+s+odnímatelným+ob\u011Bhovým+\u010Derpadlem

Katalogové číslo: (PRSIXW-7340)

Dodavatel: ProSci Inc.

Popis: Leptin; leptin (murine obesity homolog); obesity. Leptin, a product of the Obese (ob) gene, is a ligand for the OB receptor (OC-R). Mice with mutations of the ob gene have been found to be obese and diabetic and to have reduced activity, metabolism, and body temperature. M.W: 16,000.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (BOHLR1203-01)

Dodavatel: Bohlender

Popis: The grip position indicates if the passage is open or closed.

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (PRSI5647)

Dodavatel: ProSci Inc.

Popis: Slc37A2 Antibody: The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI96-691)

Dodavatel: ProSci Inc.

Popis: Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI3557)

Dodavatel: ProSci Inc.

Popis: CTRP1 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: CHIRAL TECHNOLOGIES

Popis: These columns are packed with Daicel’s coated polysaccharide-based chiral stationary phases (CSPs) which are manufactured by physically coating the polysaccharide derivatives onto silica matrices. Due to this manufacturing process, a choice of mobile phase components is typically narrower than with immobilised columns in order to minimise damage to the CSPs.

Katalogové číslo: (PRSI3555)

Dodavatel: ProSci Inc.

Popis: CTRP1 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI92-612)

Dodavatel: ProSci Inc.

Popis: Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signalling pathways involving OB-R in hypothalamus. In mammals, leptin is mainly produced by the adipose tissue and encodes body fat reserves, acting as a short-term satiety signal. In fish, the presence of a leptin-like peptide was first evidenced by immuno-cross-reactivity [14], and its existence was certainly demonstrated after the finding by synteny of a leptin sequence in the pufferfish.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI38-235)

Dodavatel: ProSci Inc.

Popis: Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.
Was product number XP-5712-M

Měrná jednotka: 1 * 500 µG

Akce

Katalogové číslo: (PRSI92-138)

Dodavatel: ProSci Inc.

Popis: CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: VWR Chemicals

Popis: These standards are ideal to use as control standards for COD measurements to verify that correct analysis for COD has taken place.

Bezpečnostní list Certifikáty

Katalogové číslo: (PRSIXP-5213)

Dodavatel: ProSci Inc.

Popis: Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSIXP-5211)

Dodavatel: ProSci Inc.

Popis: Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: VWR Collection

Popis: Ideální pro nádobky s nepravidelným tvarem. Konstrukce z nerezové oceli zajišťuje lepší ochranu proti korozi. Lázeň je navržená pro použití ve spojení s pískem, kousky nerezové oceli nebo netěkavými kapalinami.

Katalogové číslo: (460-0254)

Dodavatel: VWR Collection

Popis: Block heater block, VWR®, Hliníkový blok, Určeno pro: Blok vodní lázně (115x73x38 mm) , Poč. otvorů: -

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (462-0279)

Dodavatel: VWR Collection

Popis: Spirála chladicí, VWR®, Určeno pro: VWR lázně, 462-0207, 462-0208, 462-0212, 462-0213 a 462-0214

Měrná jednotka: 1 * 1 KS

Akce