Hledali jste: Chloroform-D1

Dodavatel: Merck

Popis: Methyl chloroformate, Sigma-Aldrich®

Katalogové číslo: (ENZOALX804806C100)

Dodavatel: ENZO LIFE SCIENCES

Popis: The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (ENZOALX804805C100)

Dodavatel: ENZO LIFE SCIENCES

Popis: The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Thermo Fisher Scientific

Popis: Chloroform, extra dry 99.9% stabilised, AcroSeal®

Bezpečnostní list

Katalogové číslo: (USBIF9046-01C)

Dodavatel: US Biological

Popis: Anti-FOXD1 Goat polyclonal antibody

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Abcam

Popis: Anti-CCND1 Rabbit Monoclonal Antibody [clone: SP4]

Bezpečnostní list

Katalogové číslo: (BOSSBS-3330R-A555)

Dodavatel: Bioss

Popis: Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7885R-HRP)

Dodavatel: Bioss

Popis: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: ENZO LIFE SCIENCES

Popis: Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.

Katalogové číslo: (BOSSBS-6691R-A555)

Dodavatel: Bioss

Popis: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2172R)

Dodavatel: Bioss

Popis: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2171R-A555)

Dodavatel: Bioss

Popis: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2172R-CY5)

Dodavatel: Bioss

Popis: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2172R-A488)

Dodavatel: Bioss

Popis: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6691R-CY7)

Dodavatel: Bioss

Popis: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Thermo Fisher Scientific

Popis: Chloroform 99+% stabilizovaný p.a.

Bezpečnostní list