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Popis: Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Antibody to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.
Katalogové číslo: BOSSBS-2190R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Avantor® ACE® C18-300 columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative. These columns are designed for a wide range of chromatographic applications, to provide great performance with acidic, basic and neutral molecules.
Katalogové číslo: ACE-231-0510
Měrná jednotka: 1 * 1 KS
Dodavatel: Avantor


Popis: This wall-mountable station is made of impact-resistant plastic and equipped with a transparent cover.
Katalogové číslo: 118-0398
Měrná jednotka: 1 * 1 KS
Dodavatel: Plum Safety


Popis: BMS 195614 is a neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM). It antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR but does not significantly affect nuclear receptor corepressor binding.
Katalogové číslo: CAYM16029-10
Měrná jednotka: 1 * 10 mg
Dodavatel: Cayman Chemical


Popis: The MP4-25D2 antibody is specific for human IL-4, a pleiotropic cytokine that Th2 cell differentiation, B cell proliferation and differentiation, and B cell class switching to IgE. MP4-25D2 is a neutralizing antibody and is reported to cross react with rhesus monkey IL-4.
Katalogové číslo: 20-7048-T025
Měrná jednotka: 1 * 25 Tests
Dodavatel: Tonbo Biosciences


Popis: Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes.
Katalogové číslo: BOSSBS-5802R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.
Katalogové číslo: BOSSBS-10085R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.
Katalogové číslo: BOSSBS-10085R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
Katalogové číslo: BOSSBS-9352R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes.
Katalogové číslo: BOSSBS-5802R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis. TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis.
Katalogové číslo: BOSSBS-0431R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
Katalogové číslo: BOSSBS-2787R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Katalogové číslo: BOSSBS-9358R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.
Katalogové číslo: BOSSBS-9351R-CY7
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Anti-SMPD3 Mouse Polyclonal Antibody
Katalogové číslo: USBI133579
Měrná jednotka: 1 * 50 µG
Dodavatel: US Biological


Popis: The proteasome is a multicatalytic proteinase complex which is characterised by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Katalogové číslo: BOSSBS-9354R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


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