Hledali jste: Tonbo Biosciences

Katalogové číslo: (70-5921-U100)

Dodavatel: Tonbo Biosciences

Popis: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Tonbo Biosciences

Popis: The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).

Katalogové číslo: (35-8030-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Human IgM (mu chain) - Affinity Pure, FITC Conjugate, min x w/human IgA + IgG

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (72-8062-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/bovine, goat, human, rabbit or rat IgG

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (30-8075-M001)

Dodavatel: Tonbo Biosciences

Popis: Rabbit anti-Human IgM (mu chain) - Affinity Pure, Biotin Conjugate

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (50-8034-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-mouse IgG (H+L), secondary antibody, conjugated to SureLight® R-Phycoerythrin, 1mg

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (30-8067-M002)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Rabbit IgG (H&L) - Affinity Pure, Biotin Conjugate

Měrná jednotka: 1 * 2 mg

Akce

Katalogové číslo: (35-8057-U500)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Mouse IgG (H&L) - F(ab')2 fragment, FITC Conjugate, min x w/bovine, goat, human, rabbit, or rat IgG

Měrná jednotka: 1 * 0,5 mg

Akce

Katalogové číslo: (70-8064-M002)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Mouse IgM (H&L) - Affinity Pure

Měrná jednotka: 1 * 2 mg

Akce

Katalogové číslo: (72-8098-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Guinea Pig IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/bovine, chicken, goat, hamster, horse, human

Měrná jednotka: 1 * 1 mg

Akce

Dodavatel: Tonbo Biosciences

Popis: The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

Dodavatel: Tonbo Biosciences

Popis: The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells. The PC61.5 antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used for depletion of Treg cells in vivo, as well as to distinguish Treg cells from naive or conventional T cells which are CD25-.

Dodavatel: Tonbo Biosciences

Popis: The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation. The 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.</p>

Dodavatel: Tonbo Biosciences

Popis: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The SK7 antibody is a widely used phenotypic marker for human T cells. This antibody may induce T cell activation in the presence of monocytes. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Binding of clone SK7 can be blocked by an alternative Anti-Human CD3 clone, OKT3. Please choose the appropriate format for each application.

Katalogové číslo: (TNB-6611-KIT)

Dodavatel: Tonbo Biosciences

Popis: The APO-DIRECT™ reagent kit provides a two color TUNEL (Terminal deoxynucleotide transferase dUTP Nick End Labelling) assay for labeling DNA breaks and total cellular DNA to detect apoptotic cells by flow cytometry. The kit contains the instructions and reagents required for measuring apoptosis in cells including: positive and negative control cells for assessing reagent performance; washing, reaction and rinsing buffers for processing individual steps in the assay; terminal deoxynucleotidyl tranferase enzyme (TdT), fluorescein isothiocyanate (FITC) deoxyuridine triphosphate (FITC-dUTP) for labeling DNA breaks and PI/RNase A solution for counter staining the total DNA.

Měrná jednotka: 1 * 50 Tests

Akce

Katalogové číslo: (40-4031-U100)

Dodavatel: Tonbo Biosciences

Popis: The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.

Měrná jednotka: 1 * 100 µG

Akce