Hledali jste: 2-Chloro-6-hydroxybenzeneboronic acid

Popis: A QuantiZyme™ Assay System. Fluorogenic, non-radioactive assay designed to measure chymotrypsin-like protease activity of purified 20S proteasome. This 96-well assay is useful for screening inhibitors and modulators of the 20S proteasome.

Katalogové číslo: ENZOBMLAK7400001

Měrná jednotka: 1 * 1 KIT

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: CD40 is a 45-50 kDa type I membrane protein and a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 is also known as pb50 or CDW40.  CD40 is expressed primarily by professional antigen-presenting cells and it is also expressed on non-immune cell types. The CD40 expressed by professional antigen-presenting cells plays a critical role in co-stimulation and antigen-presenting cell activation in T cell-dependent immune responses. Signals generated through CD40 in B cells are anti-apoptotic. These signals are also required for T cell-dependent B cell activation and proliferation, isotype switching, up-regulation of costimulatory receptors, germinal center formation and memory generation. CD40 signal transduction is initiated by binding trimeric CD40 ligand (CD40L) which is found on the surface of activated T cells.  CD40 engages several signalling pathways in B cells and these include NF-kB, the mitogen-activated protein kinases p38 and c-Jun N-terminal kinase. The 62 amino acid cytoplasmic domain (CD40c) of CD40 contains two linear TNF-receptor associated factor (TRAF) binding domains. The membrane proximal site of CD40c binds TRAF6 and the membrane distal site binds TRAF1, 2 and 3. CD40c is thought to mediate the CD40-dependant signalling pathways by recruitment of TRAF to this multimerized domain. CD40 ligation has also been shown to stimulate iNOS expression, and therefore NO production, by activating NF-kB in IFN-g treated microglial cells. NO derived from microglia has been implicated in the damage of myelin-producing oligodendrocytes in demyelinating disorders like multiple sclerosis (MS) and neuronal death during Alzheimer’s disease and brain trauma. Increased CD40-CD40 ligation has been implicated in the pathogenesis of several autoimmune inflammatory diseases, such as MS, arthritis and insulin-dependant diabetes.

Katalogové číslo: ENZOADICSS180D

Měrná jednotka: 1 * 50 µG

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: ACE1 (angiotensin converting enzyme-1, ACE) is a key regulator of blood pressure.

Katalogové číslo: ENZOBMLSA4620100

Měrná jednotka: 1 * 100 µG

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Concentrated lysis buffer for preparation of cell and tissue extracts.

Katalogové číslo: ENZOADI801502

Měrná jednotka: 1 * 10 mL

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Inhibits bacterial cell wall synthesis. Effective against Gram-negative and Gram-positive bacteria.

Katalogové číslo: ENZOALX380271G001

Měrná jednotka: 1 * 1 g

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Recommended Applications: Flow Cytometry, IHC (FS), Internalization

Species reactivity: Human, Dog

Katalogové číslo: ENZOENZABS2420100

Měrná jednotka: 1 * 100 µG

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Produced in insect cells. Full length active PKCa (protein kinase C alpha) is fused at the N-terminus to a GST-tag.

Katalogové číslo: ENZOBMLSE4940005

Měrná jednotka: 1 * 5 µG

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Most sensitive (0,088pmol/m) colorimetric kit for extracellular cGMP quantification.

Katalogové číslo: ENZOADI900013

Měrná jednotka: 1 * 1 KIT

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Activator of CB1 receptor and TRPV1

Katalogové číslo: ENZOBMLVR1040025

Měrná jednotka: 1 * 25 mg

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: For the quantitative determination of 15(S)-HETE in culture supernatants, plasma, serum, and urine from any species.

Katalogové číslo: ENZOADI900051

Měrná jednotka: 1 * 1 KIT

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Cytochalasin A

Katalogové číslo: ENZOALX380057M010

Měrná jednotka: 1 * 10 mg

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Lignan derivative with antitumor activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic activity and is an antagonist for platelet activating factor and Ca²⁺.

Katalogové číslo: ENZOALX350318M025

Měrná jednotka: 1 * 25 mg

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Calpain inhibitor

Katalogové číslo: ENZOBMLPI1000025

Měrná jednotka: 1 * 25 mg

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: The Angiotensin II ELISA Kit is a colorimetric, competitive immunoassay kit for the quantitative determination of species independent Angiotensin II in plasma and serum samples.

Katalogové číslo: ENZOADI900204

Měrná jednotka: 1 * 1 KIT

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Produced in <i>E. coli</i>. Non-glycosylated protein, containing 289 amino acids.

Katalogové číslo: ENZOALX2018140020

Měrná jednotka: 1 * 20 µG

Dodavatel: ENZO LIFE SCIENCES

Akce

Popis: Geranylgeranylpyrophosphate precursor and apoptosis inducer.

Katalogové číslo: ENZOBMLG2430020

Měrná jednotka: 1 * 20 mg

Dodavatel: ENZO LIFE SCIENCES

Akce