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Anti-KLRF1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-2681R)

Dodavatel: Bioss

Popis: KLRF1 is involved in the natural killer mediated cytolysis of PHA-induced lymphoblasts.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-ZNT8 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-15382R)

Dodavatel: Bioss

Popis: Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-KLHL36 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-9628R)

Dodavatel: Bioss

Popis: C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-C17ORF82 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-9649R)

Dodavatel: Bioss

Popis: C17orf82 is a 251 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Měrná jednotka: 1 * 100 µl

Akce