Hledali jste: lad1

Katalogové číslo: (ANTIA95533-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to GAD1 + GAD2 for WB, IHC and ELISA with samples derived from Human and Mouse.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI3763P)

Dodavatel: ProSci Inc.

Popis: LSD1 peptide is used for blocking the activity of LSD1 antibody.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI3163P)

Dodavatel: ProSci Inc.

Popis: Bcl-B peptide is used for blocking activity of Bcl-B antibody.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (BOSSBS-1302R-A350)

Dodavatel: Bioss

Popis: Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI040791-HRP)

Dodavatel: US Biological

Popis: Anti-RAD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI035670-AP)

Dodavatel: US Biological

Popis: Anti-FLAD1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (ANTIA306444-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to MAD1L1/MAD1 for WB with samples derived from Human.

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (ANTIA11251-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to PADI1 / PAD1 for WB with samples derived from human, mouse and rat.

Měrná jednotka: 1 * 100 µl

New Product Akce

Dodavatel: ELTEN

Popis: ESD ladies safety shoe, GHOST, available in white finish.

Katalogové číslo: (ANTIA306723-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to KDM1 / LSD1 for WB, IHC and ICC/IF with samples derived from Human, Mouse and Rat.

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (BOSSBS-13263R-A350)

Dodavatel: Bioss

Popis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIL4595-50E)

Dodavatel: US Biological

Popis: Anti-KDM1A Mouse Monoclonal Antibody [clone: 8A207]

Měrná jednotka: 1 * 40 µG

Akce

Katalogové číslo: (BOSSBS-13263R-A647)

Dodavatel: Bioss

Popis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13263R-HRP)

Dodavatel: Bioss

Popis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1302R-A680)

Dodavatel: Bioss

Popis: Glutamic Acid Decarboxylase (GAD) catalyses the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI151491)

Dodavatel: US Biological

Popis: Anti-CERS1 Goat Polyclonal Antibody

Měrná jednotka: 1 * 100 µG

Akce