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Katalogové číslo: (PRSI55-997)
Dodavatel: ProSci Inc.
Popis: The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
Měrná jednotka: 1 * 400 µl

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Katalogové číslo: (PRSI56-320)
Dodavatel: ProSci Inc.
Popis: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Měrná jednotka: 1 * 400 µl

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Katalogové číslo: (BOSSBS-11794R-A647)
Dodavatel: Bioss
Popis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-8867R-A680)
Dodavatel: Bioss
Popis: GHRH-R is a seven transmembrane domain protein that localises to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (ANTIA310073-96)
Dodavatel: ANTIBODIES.COM
Popis: Human SLC14A1/UTE ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human SLC14A1/UTE in serum, plasma, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

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Katalogové číslo: (ANTIA74994-96)
Dodavatel: ANTIBODIES.COM
Popis: Human SLC14A1/UTE ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human SLC14A1/UTE in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

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Katalogové číslo: (PRSI27-779)
Dodavatel: ProSci Inc.
Popis: POU3F1 is a member of the POU domain family of proteins, and regulates events during neurogenesis and myelination.
Měrná jednotka: 1 * 100 µG


Katalogové číslo: (PRSI28-705)
Dodavatel: ProSci Inc.
Popis: POU2F1 is a member of the POU family that represents the double-stranded DNA binding proteins specifically binding to the block C region.
Měrná jednotka: 1 * 100 µG


Katalogové číslo: (PRSI28-880)
Dodavatel: ProSci Inc.
Popis: POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.
Měrná jednotka: 1 * 50 µG


Katalogové číslo: (PRSI27-337)
Dodavatel: ProSci Inc.
Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Měrná jednotka: 1 * 50 µG


Katalogové číslo: (PRSI27-336)
Dodavatel: ProSci Inc.
Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Měrná jednotka: 1 * 100 µG


Katalogové číslo: (PRSI25-055)
Dodavatel: ProSci Inc.
Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Měrná jednotka: 1 * 50 µG


Katalogové číslo: (PRSI27-626)
Dodavatel: ProSci Inc.
Popis: POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes. Studies have cloned and sequenced cDNAs encoding a novel mouse POU domain protein, Oct-11, that is closely related within the POU domain to the POU class II proteins, Oct-1 and Oct-2.
Měrná jednotka: 1 * 100 µG


Katalogové číslo: (PRSI77-024)
Dodavatel: ProSci Inc.
Popis: The EM92 monoclonal antibody reacts with human and mouse Oct 3/4, a POU family transcription factor. Oct 3/4 is encoded by the Pou5F1 gene and expressed on undifferentiated cells and lost in adult tissue. Fbx15, FGF-4, NANOG, Rex1, and UTF1 expression is regulated with Oct 3/4 and in many cases gene expression is regulated in concert with Sox2.
Měrná jednotka: 1 * 0,1 mg

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Katalogové číslo: (PRSI28-937)
Dodavatel: ProSci Inc.
Popis: POU4F1 is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages.BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages (Gerrero et al., 1993).
Měrná jednotka: 1 * 100 µG


Katalogové číslo: (PRSI31-236)
Dodavatel: ProSci Inc.
Popis: POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm
Měrná jednotka: 1 * 100 µG


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