Hledali jste: Ubiquinone-5

Katalogové číslo: (ENZOALX270294M002)

Dodavatel: ENZO LIFE SCIENCES

Popis: Ubiquinone-5 ≥95% (by HPLC)

Měrná jednotka: 1 * 2 mg

New Product Akce

Dodavatel: Cayman Chemical

Popis: This Ubiquinone including CoQ1, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.

Katalogové číslo: (ENZOALX270295M002)

Dodavatel: ENZO LIFE SCIENCES

Popis: MPTP inhibitor

Měrná jednotka: 1 * 2 mg

New Product Akce

Katalogové číslo: (BOSSBS-6551R-CY7)

Dodavatel: Bioss

Popis: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6551R-A647)

Dodavatel: Bioss

Popis: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11734R)

Dodavatel: Bioss

Popis: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11734R-A647)

Dodavatel: Bioss

Popis: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11734R-A750)

Dodavatel: Bioss

Popis: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidising NADH that is produced in the Krebs cycle, this complex utilises the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest Zince defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterised by bilaterally symmetrical necrotic lesions in subcortical brain regions.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3960R)

Dodavatel: Bioss

Popis: The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3960R-A350)

Dodavatel: Bioss

Popis: The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5068R-CY5.5)

Dodavatel: Bioss

Popis: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-8530R-CY5.5)

Dodavatel: Bioss

Popis: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3971R-CY3)

Dodavatel: Bioss

Popis: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ENZOALX380235M002)

Dodavatel: ENZO LIFE SCIENCES

Popis: Antibiotic. Specific and potent inhibitor of NADH-ubiquinone oxidoreductase (complex I) that binds to ubiquinone binding site(s). Inhibits both mitochondrial and bacterial NADH ubiquinone oxidoreductase. Anticancer agent that prevents up-regulation of GRP78, and exhibits cytotoxic activity for etoposide resistant cancer cells under glucose-deprived conditions.

Měrná jednotka: 1 * 2 mg

New Product Akce

Katalogové číslo: (BOSSBS-4063R-A680)

Dodavatel: Bioss

Popis: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4063R-A647)

Dodavatel: Bioss

Popis: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Měrná jednotka: 1 * 100 µl

Akce