Hledali jste: Thio-NAD

Dodavatel: Apollo Scientific

Popis: Purity determined enzymatic method (ADH).

Dodavatel: ENZO LIFE SCIENCES

Popis: Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).

New Product

Dodavatel: PanReac AppliChem

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma)

Katalogové číslo: (USBIA3577-90A-FITC)

Dodavatel: US Biological

Popis: Anti-ART1, ID GPI-linked NAD Rabbit Polyclonal Antibody (FITC (Fluorescein))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA3577-90A-APC)

Dodavatel: US Biological

Popis: Anti-ART1, ID GPI-linked NAD Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Měrná jednotka: 1 * 200 µl

Akce

Dodavatel: Apollo Scientific

Popis: β-Nicotinamide adenine dinucleotide ≥97%

Certifikáty

Katalogové číslo: (USBIA3577-90A-HRP)

Dodavatel: US Biological

Popis: Anti-ART1, ID GPI-linked NAD Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (BOSSBS-3946R-CY5.5)

Dodavatel: Bioss

Popis: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIA3577-90A-AP)

Dodavatel: US Biological

Popis: Anti-ART1, ID GPI-linked NAD Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (BOSSBS-9456R-CY3)

Dodavatel: Bioss

Popis: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (LIOF10132)

Dodavatel: LIOFILCHEM S.R.L.

Popis: Mueller Hinton fastidious agar (Horse blood 5% + 20 mg/L β-NAD) is recommended by EUCAST for antimicrobial susceptibility testing of <i>Streptococcus spp</i> (including <i>S. pneumoniae</i>), <i>Haemophilus spp</i> and several other fastidious organisms.

Měrná jednotka: 1 * 20 KS

New Product Akce

Katalogové číslo: (BOSSBS-2388R)

Dodavatel: Bioss

Popis: Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0272R-A488)

Dodavatel: Bioss

Popis: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0273R-A680)

Dodavatel: Bioss

Popis: catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3946R-A488)

Dodavatel: Bioss

Popis: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3946R-A750)

Dodavatel: Bioss

Popis: Isocitrate dehydrogenases catalyse the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localise to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyse the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Měrná jednotka: 1 * 100 µl

Akce