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VAS-2870 ≥98% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES

BMLEI3950010 BMLEI3950050
ENZOBMLEI3950010EA 3830 CZK
ENZOBMLEI3950010 ENZOBMLEI3950050
VAS-2870 ≥98% (by HPLC)
VAS-2870

Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).


  • NADPH oxidase inhibitor


White to off-white solid.


Soluble in DMSO (up to 10mg/ml) or DMF (up to 25mg/ml).

Vzorec: C₁₈H₁₂N₆OS
Storage Temperature: Ambient
MDL Number: MFCD03407188
CAS číslo: 722456-31-7
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=8019c862ada7cae4de1f848a97f60f19d4e74205&vid=1020575d9652297968d852d5d6587908f6e94a39&prid=web&clid=SAPDAM

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