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Katalogové číslo: (BOSSBS-9037R-CY5.5)
Dodavatel: Bioss
Popis: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Měrná jednotka: 1 * 100 µl


Dodavatel: UVEX
Popis: Robustní a pohodlné antistatické zimní kotníkové boty, s vnitřním zipem, tvořené z voděodolného koženého svršku,z měkkého polstrovaného límce a polstrovaného jazyka, odolného k průniku prachu, z podrážky PUR dvojí hustoty, samočistící a protiskluzové (4,5 mm, tepelně odolné 120 °C, odolné oleji a benzínu, bez obsahu silikonu).

Katalogové číslo: (H27782.06)
Dodavatel: Thermo Fisher Scientific
Popis: N-Boc-4-oxo-L-proline methyl ester 97%
Měrná jednotka: 1 * 5 g

Katalogové číslo: (ENZOALX350109MC05)
Dodavatel: ENZO LIFE SCIENCES
Popis: Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
Měrná jednotka: 1 * 0,5 mg


Dodavatel: VWR Collection
Popis: Urine straws, 90 mm long, VWR®

Katalogové číslo: (BOSSBS-5899R-A750)
Dodavatel: Bioss
Popis: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-4206R-CY5)
Dodavatel: Bioss
Popis: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-5899R-A555)
Dodavatel: Bioss
Popis: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Měrná jednotka: 1 * 100 µl


Dodavatel: ELTEN
Popis: 100% nekožená, sportovní a lehká bezpečnostní obuv ESD bez kovů, vyrobená z nesmáčivého mikrovlákna a textilie CORDURA® s vodu odpuzujícími vlastnostmi (odolná proti protržení a oděruvzdorná, odpuzující nečistoty a vodu), polstrovaný jazyk, protiskluzová podrážka (Trainers) s dvojitou hustotou TPU/PU.

Environmentally Preferable

Katalogové číslo: (BOSSBS-4251R)
Dodavatel: Bioss
Popis: PHD1 catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins and hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. It may play a role in cell growth regulation.
Měrná jednotka: 1 * 100 µl


Dodavatel: ELTEN
Popis: ESD safety ankle shoes made from wear resistant breathable cowhide leather with fabric lining, reflective materials, a full padded bellows tongue and a dual density rubber/PU sole ERGO-ACTIVE 2.

Environmentally Preferable

Katalogové číslo: (NOVUNB100-56708)
Dodavatel: Novus Biologicals
Popis: The Caspase-3 Antibody (31A1067) - (Pro and Active) from Novus Biologicals is a mouse monoclonal antibody to Caspase-3. This antibody reacts with human, mouse, rat, porcine, chinese hamster, mammal. The Caspase-3 Antibody (31A1067) - (Pro and Active) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Electron Microscopy, CyTOF-ready.
Měrná jednotka: 1 * 0,1 mg


Dodavatel: Tonbo Biosciences
Popis: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

Dodavatel: Biotium
Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Katalogové číslo: (BOSSBS-7685R-CY3)
Dodavatel: Bioss
Popis: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-7685R-A647)
Dodavatel: Bioss
Popis: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Měrná jednotka: 1 * 100 µl


Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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