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Image Unavailable-BOSSBS-6864R-CY7

Anti-NLRP12 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-6864R-CY7)
Dodavatel: Bioss
Popis: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6864R-HRP

Anti-NLRP12 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-6864R-HRP)
Dodavatel: Bioss
Popis: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6864R

Anti-NLRP12 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-6864R)
Dodavatel: Bioss
Popis: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-81806-10G-F

1-Propanesulphonic acid sodium salt monohydrate ≥99.0% (by titrimetric analysis) for ion pair chromatography, Supelco®

Katalogové číslo: (81806-10G-F)
Dodavatel: Merck
Popis: 1-Propanesulphonic acid sodium salt monohydrate ≥99.0% (by titrimetric analysis) for ion pair chromatography, Supelco®
Měrná jednotka: 1 * 10 g
Product Image-ACRO343800250

1-Butanesulphonic acid sodium salt 99+% for HPLC

Dodavatel: Thermo Fisher Scientific
Popis: 1-Butanesulphonic acid sodium salt 99+% for HPLC

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Product Image-33615.268

Citronan sodný dihydrát ≥99%, Gen-Apex for molecular biology

Katalogové číslo: (33615.268)
Dodavatel: VWR Chemicals
Popis: Citronan sodný dihydrát ≥99%, Gen-Apex for molecular biology
Měrná jednotka: 1 * 500 g

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Product Image-ACRO327661000

MOPS 99.5% for molecular biology, for peptide sequencing DNase-, RNase-, protease-free

Dodavatel: Thermo Fisher Scientific
Popis: MOPS 99.5% for molecular biology, for peptide sequencing DNase-, RNase-, protease-free

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Product Image-ACRO218750025

Síran sodný, anhydrous 99+%, powder p.a.

Dodavatel: Thermo Fisher Scientific
Popis: Síran sodný, anhydrous 99+%, powder for analysis

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Image Unavailable-BOSSBS-12155R-A488

Anti-CCND3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-12155R-A488)
Dodavatel: Bioss
Popis: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11970R-FITC

Anti-SIX3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-11970R-FITC)
Dodavatel: Bioss
Popis: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain. Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, and is maintained in the eye throughout the entire period of fetal development. At 20 weeks of gestation, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer. Six3 maps to human chromosome 2p16-p21, between genetic markers D2S119 and D2S288. The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11970R-A350

Anti-SIX3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-11970R-A350)
Dodavatel: Bioss
Popis: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain. Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, and is maintained in the eye throughout the entire period of fetal development. At 20 weeks of gestation, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer. Six3 maps to human chromosome 2p16-p21, between genetic markers D2S119 and D2S288. The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-CY5

Anti-HSD17B4 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-11296R-CY5)
Dodavatel: Bioss
Popis: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13280R-A680

Anti-RASA1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-13280R-A680)
Dodavatel: Bioss
Popis: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
Měrná jednotka: 1 * 100 µl
Product Image-662-7379

Kombinované iontově selektivní elektrody, série 800

Dodavatel: WTW
Popis: These easy-to-use, robust, high quality ion-selective electrodes are ideal for field applications.

Image Unavailable-73575-250G

Chlorid sodný ≥99.5% for HPLC, Fluka™

Katalogové číslo: (73575-250G)
Dodavatel: Honeywell Chemicals
Popis: Chlorid sodný ≥99.5% for HPLC, Fluka™
Měrná jednotka: 1 * 250 g

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Product Image-7396-06

Hydrogenuhličitan sodný 99.0-100.5% (by acidimetry on anhydrous substance), powder USP, FCC for haemodialysis, Macron Fine Chemicals™

Dodavatel: MACRON AVANTOR BRAND
Popis: pH adjusters are used to adjust the pH of formulations.

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Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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