Hledali jste: SPDP+(N-Succinimidyl-3-(2-pyridyldithio)propionate)

Dodavatel: Apollo Scientific

Popis: Primary amine & Sulphhydryl reactiveThiolation -CleavableRef: Cumber,J.Aet al(1985)Methods Enzymol.112, 207-224

New Product

Katalogové číslo: (PIER21857)

Dodavatel: Thermo Fisher Scientific

Popis: Thermo Scientific Pierce SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Měrná jednotka: 1 * 50 mg

Certifikáty Akce

Katalogové číslo: (APOSBICL209-100MG)

Dodavatel: Apollo Scientific

Popis: Water soluble -Spacer arm-SPDPantibody-toxin conjugationRef: Carlsson,J. et al (1978) Biochem.J. 173, 723-737

Měrná jednotka: 1 * 100 mg

Akce

Katalogové číslo: (APOSBICL208-100MG)

Dodavatel: Apollo Scientific

Popis: Spacer arm SPDPantibody-toxin conjugation

Měrná jednotka: 1 * 100 mg

Akce

Katalogové číslo: (SIAL803316-50MG)

Dodavatel: Merck

Popis: The SPDP reagents are a unique group of amine- and sulfhydryl-reactive heterobifunctional crosslinkers. Whether they are used to form amine-to-amine or amine-to-sulfhydryl crosslinks among molecules, the SPDP reagents produce disulfide-containing linkages that can be cleaved later with reducing agents such as dithiothreitol (DTT).

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (PIER21650)

Dodavatel: Thermo Fisher Scientific

Popis: Thermo Scientific Pierce Sulfo-LC-SPDP is a water-soluble, long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteines.

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (APOSBICL225-50MG)

Dodavatel: Apollo Scientific

Popis: Sulphhydryl reactive -Carbohydrate reactive Cleavable

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (SIAL803472-50MG)

Dodavatel: Merck

Popis: SMPT is a heterobifunctional sulfhydryl- and amine-reactive cross-linker. SMPT is used often for conjugating a toxin molecule to a monoclonal antibody directed against a cell-surface antigen. These immunotoxins produced with SMPT are highly potent as the cleavable disulfide imparts increased cytotoxicity compared to conjugates without a cleavable bond, such as those produced with SPDP. Also, next to the pyridine-2-thione in the spacer arm are a benzene ring and a methyl group adjacent to a carbon that hinders the disulfide bond, allowing exceptional conjugate stability in vivo. SMPT has the added benefit of being more stable to hydrolysis in aqueous solutions than other NHS cross-linkers.

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (PIER21651)

Dodavatel: Thermo Fisher Scientific

Popis: Thermo Scientific Pierce LC-SPDP is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (SIAL803642-50MG)

Dodavatel: Merck

Popis: The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures.

Měrná jednotka: 1 * 50 mg

Akce

Katalogové číslo: (APOSOR322800-100MG)

Dodavatel: Apollo Scientific

Popis: SBAP (Succinimidyl 3-(bromoacetamido)propionate)

Měrná jednotka: 1 * 100 mg

Akce

Katalogové číslo: (BC07)

Dodavatel: G-Biosciences

Popis: Dithiobis(succinimidyl propionate) Homobifunctional Cross Linker.

Měrná jednotka: 1 * 1 g

Akce

Katalogové číslo: (APOSBICL102-1G)

Dodavatel: Apollo Scientific

Popis: Primary amine reactive -Thiol cleavable.

Měrná jednotka: 1 * 1 g

Akce

Katalogové číslo: (90089.)

Dodavatel: Biotium

Popis: 5-ROX-PEO8 SE (full name: 5-Carboxy-X-rhodamine-PEO8-propionate, succinimidyl ester) has an approximately 32 Angstrom water-soluble PEG spacer that separates the red fluorescent ROX dye and the amine-reactive SE group.

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (90081.)

Dodavatel: Biotium

Popis: 5-CR110-PEO4 SE (full name: 5-Carboxyrhodamine 110-PEO4-propionate, succinimidyl ester, single isomer) is an excellent green fluorescent rhodamine dye for labeling amines.

Měrná jednotka: 1 * 5 mg

Akce

Katalogové číslo: (90085.)

Dodavatel: Biotium

Popis: 5-FAM-PEO8 SE (full name: 5-Carboxyfluorescein-PEO8 propionate succinimidyl ester) has an approximately 32 Angstrom water-soluble PEG spacer that separates fluorescein and the amine-reactive SE group.

Měrná jednotka: 1 * 1 mg

Akce