Hledali jste: Peracetyl+maltoheptaose,+anomeric+mixture

Dodavatel: Apollo Scientific

Popis: Peracetyl maltoheptaose, anomeric mixture

Dodavatel: Apollo Scientific

Popis: Peracetyl maltohexaose, anomeric mixture

Dodavatel: Apollo Scientific

Popis: Peracetyl maltooctaose, anomeric mixture

Dodavatel: Thermo Scientific

Popis: D-(-)-Lyxose mixture of anomers 99+%

Bezpečnostní list

Dodavatel: Apollo Scientific

Popis: Activator of phosphorylase B for the preparation of heptulose-2-phosphate.

Dodavatel: Merck

Popis: Maltoheptaose, Sigma-Aldrich®

Katalogové číslo: (BNUM0937-50)

Dodavatel: Biotium

Popis: Recognizes a disaccharide epitope, Gal1-3GalNAc, of Thomsen-Friedenreich (TF) antigen. It is specific for both anomeric forms of the disaccharide (TF and TF, including related structures on the glycolipid) and shows no cross-reactivity with sialylated glycophorin. The Thomsen-Friedenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or malignancy. It is considered as a pan-carcinoma marker. This MAb is capable to agglutinate desialylated red blood cells. During metastasis, the ability of malignant cells to form multicellular aggregates via homotypic or heterotypic aggregation and their adhesion to the endothelium are critical. The tumor-associated carbohydrate Thomsen-Friedenreich antigen (Gal-GalNAc) is involved in tumor cell adhesion and tissue invasion. It also causes an immune response, and overexpression of the antigen causes cancer cells to be more sensitive to natural killer cell lysis. The Thomsen-Friedenreich antigen is suppressed in normal healthy cells and represents one of the few chemically well-defined antigens associated with tumor malignancy. The presence of the Thomsen-Friedenreich antigen on the surface of cancer cells may result from a divergence from the normal pathway for O-linked glycosylation in these cells, most likely caused by inappropriate localization of the enzymes involved in synthesis of the disaccharide.

Měrná jednotka: 1 * 50 µl

Akce

Dodavatel: Biotium

Popis: Recognizes a disaccharide epitope, Gal1-3GalNAc, of Thomsen-Friedenreich (TF) antigen. It is specific for both anomeric forms of the disaccharide (TF and TF, including related structures on the glycolipid) and shows no cross-reactivity with sialylated glycophorin. The Thomsen-Friedenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or malignancy. It is considered as a pan-carcinoma marker. This MAb is capable to agglutinate desialylated red blood cells. During metastasis, the ability of malignant cells to form multicellular aggregates via homotypic or heterotypic aggregation and their adhesion to the endothelium are critical. The tumor-associated carbohydrate Thomsen-Friedenreich antigen (Gal-GalNAc) is involved in tumor cell adhesion and tissue invasion. It also causes an immune response, and overexpression of the antigen causes cancer cells to be more sensitive to natural killer cell lysis. The Thomsen-Friedenreich antigen is suppressed in normal healthy cells and represents one of the few chemically well-defined antigens associated with tumor malignancy. The presence of the Thomsen-Friedenreich antigen on the surface of cancer cells may result from a divergence from the normal pathway for O-linked glycosylation in these cells, most likely caused by inappropriate localization of the enzymes involved in synthesis of the disaccharide.

Katalogové číslo: (PRSI56-189)

Dodavatel: ProSci Inc.

Popis: The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans.

Měrná jednotka: 1 * 400 µl

New Product Akce

Dodavatel: MP Biomedicals

Popis: D-(+)-Maltose monohydrate is a component of starch and glycogen. It is a sugar composed of 2 α-D-glucose molecules coupled by an α(1→4) glycosidic bond. It is a reducing sugar with one anomeric carbon not linked in an anomeric bond. It contains a hemiacetal function and can mutarotate. Maltose is one product generated from starch and glycogen by the action of α-amylase.

Bezpečnostní list

Dodavatel: MP Biomedicals

Popis: Storage: Store at room Temperature (15-30 °C)
Sucrose is a nonreducing disaccharide composed of glucose and fructose, linked via their anomeric carbons. It is obtained commercially from Sugarcane, sugar beet (Beta vulgaris), and other plants and used extensively as a food and a sweetener.
Use to create sucrose gradients for purification of viruses and proteins.

Katalogové číslo: (PRSI33-533)

Dodavatel: ProSci Inc.

Popis: Recognises a disaccharide epitope, Gal1-3GalNAc, of Thomsen-Friedenreich (TF) antigen. It is specific for both anomeric forms of the disaccharide (TF and TF, including related structures on the glycolipid) and shows no cross-reactivity with sialylated glycophorin. The Thomsen-Friedenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or malignancy. It is considered as a pan-carcinoma marker. During metastasis, the ability of malignant cells to form multicellular aggregates via homotypic or heterotypic aggregation and their adhesion to the endothelium are critical. The tumor-associated carbohydrate Thomsen-Friedenreich antigen (Gal-GalNAc) is involved in tumor cell adhesion and tissue invasion. It also causes an immune response, and overexpression of the antigen causes cancer cells to be more sensitive to natural killer cell lysis. The Thomsen-Friedenreich antigen is suppressed in normal healthy cells and represents one of the few chemically well-defined antigens associated with tumor malignancy. The presence of the Thomsen-Friedenreich antigen on the surface of cancer cells may result from a divergence from the normal pathway for O-linked glycosylation in these cells, most likely caused by inappropriate localization of the enzymes involved in synthesis of the disaccharide.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-541)

Dodavatel: ProSci Inc.

Popis: Recognises a disaccharide epitope, Gal1-3GalNAc, of Thomsen-Friedenreich (TF) antigen. It is specific for both anomeric forms of the disaccharide (TF and TF, including related structures on the glycolipid) and shows no cross-reactivity with sialylated glycophorin. The Thomsen-Friedenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or malignancy. It is considered as a pan-carcinoma marker. During metastasis, the ability of malignant cells to form multicellular aggregates via homotypic or heterotypic aggregation and their adhesion to the endothelium are critical. The tumor-associated carbohydrate Thomsen-Friedenreich antigen (Gal-GalNAc) is involved in tumor cell adhesion and tissue invasion. It also causes an immune response, and overexpression of the antigen causes cancer cells to be more sensitive to natural killer cell lysis. The Thomsen-Friedenreich antigen is suppressed in normal healthy cells and represents one of the few chemically well-defined antigens associated with tumor malignancy. The presence of the Thomsen-Friedenreich antigen on the surface of cancer cells may result from a divergence from the normal pathway for O-linked glycosylation in these cells, most likely caused by inappropriate localization of the enzymes involved in synthesis of the disaccharide.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (VWRS5923.2500)

Dodavatel: VWR Collection

Popis: Dichloromethane : Methanol mixture (50:50) (v/v)

Měrná jednotka: 1 * 2,5 L

Akce

Katalogové číslo: (92504.290)

Dodavatel: VWR Chemicals

Popis: Selenium reagent mixture for the determination of nitrogen acc. to Wieninger

Měrná jednotka: 1 * 1 kg

Bezpečnostní list Akce

Katalogové číslo: (VWRS83977.460)

Dodavatel: VWR Collection

Popis: Powder mixture mud II

Měrná jednotka: 1 * 25 kg

Bezpečnostní list Certifikáty Akce