Hledali jste: 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde

Dodavatel: VWR Chemicals

Popis: Kyselina šťavelová dihydrát 99.5-102.5%, AnalaR NORMAPUR® Reag. Ph. Eur., ACS analytical reagent

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Dodavatel: Apollo Scientific

Popis: Holmium trichloride hexahydrate 98%

Dodavatel: Apollo Scientific

Popis: Decaethylene glycol

Dodavatel: Thermo Fisher Scientific

Popis: Calcium phosphate tribasic (34 - 40% Ca)

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Dodavatel: VWR Chemicals

Popis: Kyselina 5-sulfosalicylová dihydrát ≥99%, AnalaR NORMAPUR® analytical reagent

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Dodavatel: Avantor

Popis: Kyselina 5-sulfosalicylová dihydrát 99.0-101.0%, BAKER ANALYZED® ACS, J.T.Baker®

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Katalogové číslo: (41908.04)

Dodavatel: Thermo Fisher Scientific

Popis: Hafnium(IV) tert-butoxide ≥99.9% (metals basis excluding Zr) (max. 0.5% Zr)

Měrná jednotka: 1 * 2 g

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Katalogové číslo: (ENZOADIOSA400E)

Dodavatel: ENZO LIFE SCIENCES

Popis: Cleavage of heme b (Fe-protoporphyrin IX) at the a-methene carbon bridge to form the open tetrapyrrole, biliverdin IXa and carbon monoxide (CO) is catalyzed by heme oxygenase (HO) isozymes HO-1 and HO-2 (heme hydrogen-donor: oxygen oxidoreductase; EC 1.14.99.3). In mammalian species, biliverdin reductase (BVR; bilirubin: NAD(P)+ oxidoreductase; EC 1.3.1.24) converts the open tetrapyrrole to bilirubin. This pathway represents the only efficient way of making bilirubin and thereby deterring activation of oxygen by the heme molecule. HO-1 belongs to the heat shock protein family (Hsp32), while HO-2 takes a constitutive form expressed at exceedingly high levels in the brain and testes. The end products of the heme degradation process carry out important physiological activities. CO may act as a messenger in the brain and systemic organs stimulating cGMP-production through interactions with the heme-dependent form of guanylate cyclase. Bile pigments display potent antioxidant activity as well as effective antiviral activity against HIV and herpes virus. BVR is unique among all enzymes characterized to date in having two pH optima (6.8 and 8.7), using a different cofactor at each pH range (NADH at pH 7.0 and NADPH at pH 8.7). The enzyme displays pI and molecular mass microheterogeneity, apparently a result of post translational modifications. In rat, the enzyme also shows a tissue specific developmental pattern. BVR is not inactivated by heat shock, and its preexisting message is not sequestered from translation subsequent to thermal stress. Furthermore, reductase preserves microheterogeneity under thermal stress. BVR expression occurs not only in cells and brain regions that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. Rat cDNA for BVR has been isolated and characterized. The deduced protein contains 3 cysteine residues (Cys73, Cys281, and Cys290) involved in cofactor and substrate binding. Human BVR consists of a substantially longer polypeptide than the rat enzyme (41-42 kDa vs. 33 kDa), but also is dual cofactor and dual pH dependent, requires free SH groups for activity, and displays pI and molecular mass microheterogeneity. The human and rat BVR share some antigenic epitopes and show immunochemical cross reactivity.

Měrná jednotka: 1 * 100 µG

Akce

Dodavatel: Thermo Fisher Scientific

Popis: Kyselina šťavelová dihydrát 99.5-102.5% ACS

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Katalogové číslo: (BOSSBS-1238R)

Dodavatel: Bioss

Popis: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1238R-A750)

Dodavatel: Bioss

Popis: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (59004.)

Dodavatel: Biotium

Popis: Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic dye molecules such as cell-permeable AM esters of Fura-2, Fluo-3, Indo-1, or Rhod-2 calcium indicators to facilitate cell loading.

Měrná jednotka: 1 * 1 mL

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Katalogové číslo: (84793.180)

Dodavatel: VWR Chemicals

Popis: Standardy víceprvkové, Víceprvkový standard kontroly kvality 10 mg/l {Al; Ag; As; B; Ba; Ca; Cd; Ce; Co; Cr; Cu; Dy; Er; Eu; Fe; Gd; Ho; K; La; Li; Lu; Mg; Mn; Na; Nd; Ni; P; Pb; Rb; Se; Sm; Sr; Tl; Tm; V; Zn} ve 2% kyselině dusičné ARISTAR® pro ICP-MS, VWR® ARISTAR®, Aplikace: Stndardy ICP-MS

Měrná jednotka: 1 * 100 mL

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Katalogové číslo: (59005.)

Dodavatel: Biotium

Popis: Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic dye molecules such as AM esters of Fura-2, Fluo-3, Indo-1, or Rhod-2 to facilitate cell loading.

Měrná jednotka: 1 * 30 mL

Akce

Katalogové číslo: (BOSSBS-1238R-A680)

Dodavatel: Bioss

Popis: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (20350.232)

Dodavatel: VWR Chemicals

Popis: Kyselina L(+)-glutamová 98.5-100.5% Ph. Eur.

Měrná jednotka: 1 * 250 g

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