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NF-κB Activation Inhibitor III ≥99%

Dodavatel: Cayman Chemical
Popis: NF-κB Activation Inhibitor III ≥99%

Product Image-CAYM17493-1

NF-κB Inhibitor (SN50)

Dodavatel: Cayman Chemical
Popis: A synthetic peptide corresponding to the nuclear localisation sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

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DWK Life Sciences

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Image Unavailable-ENZOALX260089M005

Protease Inhibitor I aldehyde

Dodavatel: ENZO LIFE SCIENCES
Popis: Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

New Product

Image Unavailable-ENZOENZCHM1420005

Simvastatin sodium salt ≥97% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Competitive inhibitor of HMG-CoA reductase. Suppresses TNF-induced NF-κB activation.

New Product

Image Unavailable-ENZOALX350109MC05

Panepoxydone (from Lentinus crinitus) ≥95% (by HPLC, MS)

Katalogové číslo: (ENZOALX350109MC05)
Dodavatel: ENZO LIFE SCIENCES
Popis: Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
Měrná jednotka: 1 * 0,5 mg

New Product


Image Unavailable-BOSSBS-3232R-CY7

Anti-IKBKB Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-3232R-CY7)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-A488

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-6202R-A488)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-CY5

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-6202R-CY5)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-HRP

Anti-IKBKB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-3232R-HRP)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-CY5

Anti-IKBKB Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-3232R-CY5)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-A647

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-6202R-A647)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-HRP

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-6202R-HRP)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-CY3

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-6202R-CY3)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-A750

Anti-IKK beta Tyr199 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-3232R-A750)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-A680

Anti-CIKS Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-6202R-A680)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-A680

Anti-IKK beta Tyr199 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-3232R-A680)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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