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Image Unavailable-BOSSBS-15541R-A647

Anti-IDN3 Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Katalogové číslo: (BOSSBS-15541R-A647)
Dodavatel: Bioss
Popis: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterised by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9182R

Anti-VGLL1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-9182R)
Dodavatel: Bioss
Popis: VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA binding domain.
Měrná jednotka: 1 * 100 µl

Nové řešení transparentnosti pro evropské zákazníky

Všimli jste si naší nově zlepšené viditelnosti rozmístění zásob u pokladny?

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Zlepšení rozmístění zásob

Image Unavailable-BOSSBS-12397R-CY5

Anti-MAML2 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-12397R-CY5)
Dodavatel: Bioss
Popis: Notch receptors are involved in cell-fate determination in organisms as diverse as flies, frogs, and humans (1). The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2). In Drosophila, loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2). The human homolog, mastermind-like 1 (Mam1), localizes to nuclear bodies (2-4). Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, forms a DNA-binding complex with ICN and RBP-Jk, and amplifies Notch-induced transcription of Hes1 (2). Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5). The gene which encodes Mam1 maps to human chromosome 5 (4).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4278R-A647

Anti-FAT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-4278R-A647)
Dodavatel: Bioss
Popis: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-15541R-CY7

Anti-IDN3 Rabbit Polyclonal Antibody (Cy7)

Katalogové číslo: (BOSSBS-15541R-CY7)
Dodavatel: Bioss
Popis: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterised by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-15541R-CY5

Anti-IDN3 Rabbit Polyclonal Antibody (Cy5)

Katalogové číslo: (BOSSBS-15541R-CY5)
Dodavatel: Bioss
Popis: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterised by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOBMLKI1740005

Fluor-de-Lys® H4-AcK16 deacetylase Substrate

Katalogové číslo: (ENZOBMLKI1740005)
Dodavatel: ENZO LIFE SCIENCES
Popis: The deacetylated state of lysine-16 of histone H4 (H4-K16) is thought to be a critical factor in determining regions of chromatin silencing. Conversely, acetylation of lysine-16 can be associated with increased transcription, such as that due to dosage compensation from the X-chromosome of male Drosophila.
Měrná jednotka: 1 * 1 Vial

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Image Unavailable-BOSSBS-9732R-A350

Anti-ZWILCH Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-9732R-A350)
Dodavatel: Bioss
Popis: Zwilch is the human homolog of the Drosophila Zwilch protein. The Drosophila Zwilch forms a complex with both ROD Rough Deal) and ZWINT (Zeste-White 10, also designated ZW10) proteins. This complex is important for chromosome segregation because it recruits cytoplasmic Dynein to the kinetochore and plays a crucial role in the spindle checkpoint. The role of Zwilch in complex is thought to be evolutionarily conserved because the human homologs of Zwilch, ZWINT and ROD coimmunoprecipitate in a human cell line called HeLa. The human Zwilch, ZWINT and ROD complex localizes to the kinetochores at prometaphase. Mutations were discovered in Zwilch, ZWINT and ROD during a screen for mutations in alleles encoding putative chromosome instability genes in cases of human colorectal cancer. These mutations may contribute in part to the chromosomal instability phenotype of colorectal tumor cells.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9732R-A680

Anti-ZWILCH Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-9732R-A680)
Dodavatel: Bioss
Popis: Zwilch is the human homolog of the Drosophila Zwilch protein. The Drosophila Zwilch forms a complex with both ROD Rough Deal) and ZWINT (Zeste-White 10, also designated ZW10) proteins. This complex is important for chromosome segregation because it recruits cytoplasmic Dynein to the kinetochore and plays a crucial role in the spindle checkpoint. The role of Zwilch in complex is thought to be evolutionarily conserved because the human homologs of Zwilch, ZWINT and ROD coimmunoprecipitate in a human cell line called HeLa. The human Zwilch, ZWINT and ROD complex localizes to the kinetochores at prometaphase. Mutations were discovered in Zwilch, ZWINT and ROD during a screen for mutations in alleles encoding putative chromosome instability genes in cases of human colorectal cancer. These mutations may contribute in part to the chromosomal instability phenotype of colorectal tumour cells.
Měrná jednotka: 1 * 100 µl
Product Image-NOVUNB110-93596SS

Anti-SIAH1/SIAH2 Mouse Monoclonal Antibody [clone: 8G7H12]

Dodavatel: Novus Biologicals
Popis: Mouse Monoclonal SIAH1/2 Antibody (8G7H12). Tested Applications: Western Blot, Immunoprecipitation. Tested Reactivity: Human, Rat, Drosophila, Porcine, Zebrafish, Mouse (-).

Image Unavailable-BOSSBS-13601R-A680

Anti-JHDM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-13601R-A680)
Dodavatel: Bioss
Popis: KDM2 / JHD1 is a JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13601R-CY5

Anti-JHDM1 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-13601R-CY5)
Dodavatel: Bioss
Popis: KDM2 / JHD1 is a JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9182R-A750

Anti-VGLL1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-9182R-A750)
Dodavatel: Bioss
Popis: VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA binding domain.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6907R-A488

Anti-SEPT8 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-6907R-A488)
Dodavatel: Bioss
Popis: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. [provided by RefSeq, Jun 2012].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11884R-HRP

Anti-MATH2/NEUROD6 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-11884R-HRP)
Dodavatel: Bioss
Popis: The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0775R-A488

Anti-CG6856-PA Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-0775R-A488)
Dodavatel: Bioss
Popis: This clone was constructed and sequenced as part of a high-throughput process to generate expression-ready clones from the Drosophila Gene Collection for use as a proteomics resource. The clone has been full-length sequenced to verify fidelity in translation, proper reading frame and presence of a recombination site.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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