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Image Unavailable-BOSSBS-15482R-A555

Anti-hHR23b Rabbit Polyclonal Antibody (ALEXA FLUOR® 555)

Katalogové číslo: (BOSSBS-15482R-A555)
Dodavatel: Bioss
Popis: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A350

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-6634R-A350)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Product Image-UVPA95-0181-02

UV rechargeable lamps, 26 P series

Dodavatel: UVP ULTRA VIOLET PRODUCTS
Popis: Rechargeable 6-watt 26P series lamps are available in three dual-tube models. The lamps are equipped with an internal gel based, lead-acid battery, which can be charged for field operation from a standard wall outlet. Model UVSL-26P can operate with both long and shortwave on at the same time.

Image Unavailable-551-0011

Příslušenství k UV lampám a skříním

Dodavatel: CAMAG
Popis: UV filter glass for UV lamps

Image Unavailable-BOSSBS-0527R-A488

Anti-MME Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-0527R-A488)
Dodavatel: Bioss
Popis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0527R-A750

Anti-CD10 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-0527R-A750)
Dodavatel: Bioss
Popis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibres.
Měrná jednotka: 1 * 100 µl
Image Unavailable-20332-500UL

Anti-IgG Chicken Polyclonal Antibody (CF™ 350)

Katalogové číslo: (20332-500UL)
Dodavatel: Biotium
Popis: CF™350 is a blue fluorescent dye with excitation/emission maxima at 347/448nm. CF™350 is optimized for UV excitation, and is spectrally similar to AlexaFluor®350, AMCA, and DyLight®350. CF™350 is more water soluble, more photostable, and 50% brighter when conjugated to antibodies than the traditional blue dye AMCA. CF™350 antibody conjugates are comparable in brightness to AlexaFluor®350 dye conjugates.
Měrná jednotka: 1 * 0,5 mL
Image Unavailable-BOSSBS-7861R

Anti-EME1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-7861R)
Dodavatel: Bioss
Popis: EME1 complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein (MUS81) to form an endonuclease complex which cleaves branched DNA structures, especially those arising during stalled DNA replication. The protein may be involved in repairing DNA damage and in maintaining genomic stability. It interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Alternative splicing results in multiple transcript variants.
Měrná jednotka: 1 * 100 µl
Product Image-1.13203.0001

UV lamp for microbiology

Katalogové číslo: (1.13203.0001)
Dodavatel: Merck
Popis: This UV lamp is designed for use with Fluorocult® culture media.
Měrná jednotka: 1 * 1 KS

Bezpečnostní list Certifikáty


Image Unavailable-LOVI384930

Accessories for UV/Visible Spectrophotometers, XD 7000 (Vis) and XD 7500 (UV-Vis)

Dodavatel: Lovibond
Popis: Accessory for UV/Visible spectrophotometers, UV pen lamp, 254 nm

Image Unavailable-BOSSBS-7905R-CY5.5

Anti-BRSK1 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-7905R-CY5.5)
Dodavatel: Bioss
Popis: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7905R-A555

Anti-BRSK1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-7905R-A555)
Dodavatel: Bioss
Popis: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
Měrná jednotka: 1 * 100 µl
Image Unavailable-20364-500UL

Anti-IgG Chicken Polyclonal Antibody (CF™ 350)

Katalogové číslo: (20364-500UL)
Dodavatel: Biotium
Popis: CF™350 is a blue fluorescent dye with excitation/emission maxima at 347/448nm. CF™350 is optimized for UV excitation, and is spectrally similar to AlexaFluor®350, AMCA, and DyLight®350. CF™350 is more water soluble, more photostable, and 50% brighter when conjugated to antibodies than the traditional blue dye AMCA. CF™350 antibody conjugates are comparable in brightness to AlexaFluor®350 dye conjugates.
Měrná jednotka: 1 * 0,5 mL
Image Unavailable-AATB3111

mFluor™ UV 375 Biotin conjugate

Katalogové číslo: (AATB3111)
Dodavatel: AAT BIOQUEST
Popis: mFluor™ UV 375 Biotin Conjugate contains mFluor™ UV 375 fluorophore that is well excited by the common 350 nm laser.
Měrná jednotka: 1 * 1 mg

New Product


Image Unavailable-UVPA22-0084-01

Accessories for benchtop transilluminators

Dodavatel: UVP ULTRA VIOLET PRODUCTS
Popis: Transilluminator accessory

Product Image-634-1078

Spektrofotometry Vis a UV/Vis, Genesys™

Dodavatel: Thermo Fisher Scientific
Popis: Spektrofotometry Genesys Vis / UV-Vis poskytují výjimečný výkon s moderním designem.

Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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