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Image Unavailable-PRSI91-536

Human recombinant GLIPR1 (from cells)

Katalogové číslo: (PRSI91-536)
Dodavatel: ProSci Inc.
Popis: Glioma Pathogenesis-Related Protein 1 (GLIPR1) is a member of the CRISP family. It is a single-pass membrane protein with 266 amino acids. GLIPR1 is highly expressed in the lung and kidney and lowly expressed in the heart and liver. It is also highly expressed in cell lines that are derived from nervous system tumors arising from glia; conversely, it is lowly expressed in non-glial-derived nervous system tumor cell lines. GLIPR1 is only expressed in brain tumor glioblastoma multiforme/astrocytoma and not expressed in other nervous system tumors nor normal adult or fetal tissues.
Měrná jednotka: 1 * 50 µG
Product Image-PRSIXP-5103BT

Anti-TNFSF13 Rabbit Polyclonal Antibody (Biotin) [clone: ]

Katalogové číslo: (PRSIXP-5103BT)
Dodavatel: ProSci Inc.
Popis: APRIL (A PRoliferation Inducing Ligand) a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. Members of the TNF superfamily regulate immune responses and induce apoptosis.
Měrná jednotka: 1 * 50 µG

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Image Unavailable-PRSI34-061

Anti-EPCAM Mouse Monoclonal Antibody [clone: EPM17-2]

Katalogové číslo: (PRSI34-061)
Dodavatel: ProSci Inc.
Popis: EpCAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. [UniProt].
Měrná jednotka: 1 * 100 µG

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Image Unavailable-PRSI91-001

Human recombinant G-CSF (from E. coli)

Katalogové číslo: (PRSI91-001)
Dodavatel: ProSci Inc.
Popis: Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines
Měrná jednotka: 1 * 50 µG
Product Image-PRSI3091

Anti-AID Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI3091)
Dodavatel: ProSci Inc.
Popis: AID Antibody: Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.
Měrná jednotka: 1 * 100 µG
Image Unavailable-PRSI34-081

Anti-EPCAM Rabbit Monoclonal Antibody [clone: EGP40/1556R]

Katalogové číslo: (PRSI34-081)
Dodavatel: ProSci Inc.
Popis: Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. [UniProt].
Měrná jednotka: 1 * 100 µG

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Image Unavailable-PRSI76-892

Anti-LAMP1 Mouse Monoclonal Antibody [clone: H4A3] (PE (Phycoerythrin))

Katalogové číslo: (PRSI76-892)
Dodavatel: ProSci Inc.
Popis: The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.
Měrná jednotka: 1 * 25 Tests

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Image Unavailable-PRSI76-891

Anti-LAMP1 Mouse Monoclonal Antibody [clone: H4A3] (PE (Phycoerythrin))

Katalogové číslo: (PRSI76-891)
Dodavatel: ProSci Inc.
Popis: The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.
Měrná jednotka: 1 * 100 Tests

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Image Unavailable-PRSI91-236

Human recombinant HRSP12 (from E. coli)

Katalogové číslo: (PRSI91-236)
Dodavatel: ProSci Inc.
Popis: Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
Měrná jednotka: 1 * 50 µG
Image Unavailable-PRSI33-868

Anti-EPCAM Mouse Monoclonal Antibody [clone: EPM17-1]

Katalogové číslo: (PRSI33-868)
Dodavatel: ProSci Inc.
Popis: EpCAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. [UniProt].
Měrná jednotka: 1 * 100 µG

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Product Image-PRSI96-749

Human recombinant Dr51 (from HEK293 cells)

Katalogové číslo: (PRSI96-749)
Dodavatel: ProSci Inc.
Popis: Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor.
Měrná jednotka: 1 * 100 µG
Image Unavailable-PRSI76-863

Anti-Cdh5 Rat Monoclonal Antibody [clone: BV13] (PE (Phycoerythrin))

Katalogové číslo: (PRSI76-863)
Dodavatel: ProSci Inc.
Popis: The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDa type II Cadherin. CD144 is a hemophilic adhesion molecule of the endothelial cell line essential to maintaining cell layer integrity. It is involved in cell growth inhibition, migration, and survival.
Měrná jednotka: 1 * 0,1 mg

New Product


Image Unavailable-PRSI34-157

Anti-BAX Mouse Monoclonal Antibody [clone: SPM336]

Katalogové číslo: (PRSI34-157)
Dodavatel: ProSci Inc.
Popis: Recognises a protein of 21 kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Měrná jednotka: 1 * 100 µG

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Image Unavailable-PRSI92-285

Human recombinant SLP-76 (from E. coli)

Katalogové číslo: (PRSI92-285)
Dodavatel: ProSci Inc.
Popis: Lymphocyte cytosolic protein 2（LCP2）contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Měrná jednotka: 1 * 50 µG
Product Image-PRSI3409

Anti-XAF1 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI3409)
Dodavatel: ProSci Inc.
Popis: XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs.
Měrná jednotka: 1 * 100 µG
Product Image-PRSI26-405

Anti-MDM1 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI26-405)
Dodavatel: ProSci Inc.
Popis: MDM1 is a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles and is amplified in the mouse transformed 3T3 cell line, and the protein is able to bind to p53. This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles and is amplified in the mouse transformed 3T3 cell line, and the protein is able to bind to p53. In mouse several transcripts have been described for this gene which result from alternative polyadenylation, splicing and exon usage.
Měrná jednotka: 1 * 50 µG
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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