Hledali jste: Haloenol+lactone+suicide+substrate

Katalogové číslo: (BOSSBS-5324R-FITC)

Dodavatel: Bioss

Popis: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6477R-A647)

Dodavatel: Bioss

Popis: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0216R-A647)

Dodavatel: Bioss

Popis: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2959R-A488)

Dodavatel: Bioss

Popis: Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Biotium

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: (BOSSBS-0216R-A750)

Dodavatel: Bioss

Popis: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0216R-HRP)

Dodavatel: Bioss

Popis: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (APOSOR917300-5G)

Dodavatel: Apollo Scientific

Popis: Boc-D-homoserine lactone 97%

Měrná jednotka: 1 * 5 g

Akce

Dodavatel: Apollo Scientific

Popis: L-Gulofuranuronic acid, γ-lactone ≥98%

Dodavatel: Thermo Fisher Scientific

Popis: CAS No.: 1128-23-0

Bezpečnostní list

Dodavatel: Thermo Fisher Scientific

Popis: Crystal violet lactone

Bezpečnostní list Certifikáty

Katalogové číslo: (ACRO227830100)

Dodavatel: Thermo Fisher Scientific

Popis: D(+)-Ribonic acid γ-lactone 96%

Měrná jednotka: 1 * 10 g

Bezpečnostní list Akce

Dodavatel: Apollo Scientific

Popis: D-Mannofuranuronic acid, γ-lactone ≥98%

Dodavatel: Apollo Scientific

Popis: 2,3,5-Tri-O-acetyl-D-arabinonic acid, γ-lactone ≥98%

Katalogové číslo: (APOSOR46256-5G)

Dodavatel: Apollo Scientific

Popis: (+)-Corey lactone 95%

Měrná jednotka: 1 * 5 g

Akce

Dodavatel: Apollo Scientific

Popis: 2C-Methyl-D-ribono-1,4-lactone