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Image Unavailable-PRSI90-506

Human recombinant IL18 (from E. coli)

Katalogové číslo: (PRSI90-506)
Dodavatel: ProSci Inc.
Popis: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesised as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
Měrná jednotka: 1 * 10 µG
Image Unavailable-SIALA4284-100G

L(+)-Asparagin monohydrát, Sigma-Aldrich®

Dodavatel: Merck
Popis: L(+)-Asparagin monohydrát, Sigma-Aldrich®

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Product Image-M183-5MG

VWR®, Pepstatin A

Katalogové číslo: (M183-5MG)
Dodavatel: VWR Chemicals
Popis: An aspartic protease inhibitor of pepsin, renin, and cathepsin D. Can also block HIV protease. Not soluble in water.
Měrná jednotka: 1 * 5 mg

Bezpečnostní list


Image Unavailable-USBIG4003-90C

Anti-Glutamate-aspartate Transporter Rabbit polyclonal antibody

Katalogové číslo: (USBIG4003-90C)
Dodavatel: US Biological
Popis: Anti-Glutamate-aspartate Transporter Rabbit Polyclonal Antibody
Měrná jednotka: 1 * 100 µl
Image Unavailable-USBIG4003-90W

Anti-Glutamate Transporter, Aspartate EAAT1 Rabbit polyclonal antibody

Katalogové číslo: (USBIG4003-90W)
Dodavatel: US Biological
Popis: Anti-Glutamate Transporter, Aspartate EAAT1 Rabbit Polyclonal Antibody
Měrná jednotka: 1 * 100 µG
Image Unavailable-786-052

Pepstatin A

Katalogové číslo: (786-052)
Dodavatel: G-Biosciences
Popis: Pepstatin is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases. Soluble in DMSO or methanol.
Měrná jednotka: 1 * 25 mg
Image Unavailable-J62869.A1

L(+)-Asparagin monohydrát cell culture reagent

Dodavatel: Thermo Scientific
Popis: L(+)-Asparagin monohydrát cell culture reagent

Bezpečnostní list Certifikáty

Image Unavailable-SIALA7094-100G

L(+)-Asparagin monohydrát, Sigma-Aldrich®

Dodavatel: Merck
Popis: L(+)-Asparagin monohydrát, Sigma-Aldrich®

Image Unavailable-USBIG4003-91A

Anti-Glutamate/Aspartate Transporter 2 Mouse monoclonal antibody [clone: 10H26]

Katalogové číslo: (USBIG4003-91A)
Dodavatel: US Biological
Popis: Anti-Glutamate/Aspartate Transporter 2 Mouse Monoclonal Antibody [clone: 10H26]
Měrná jednotka: 1 * 100 µG
Image Unavailable-SIALA8381-100G

L(+)-Asparagin monohydrát, Sigma-Aldrich®

Dodavatel: Merck
Popis: L(+)-Asparagin monohydrát, Sigma-Aldrich®

Image Unavailable-BOSSBS-11953R-CY3

Anti-SLC25A12 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-11953R-CY3)
Dodavatel: Bioss
Popis: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11953R-CY5

Anti-SLC25A12 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-11953R-CY5)
Dodavatel: Bioss
Popis: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11953R-CY7

Anti-SLC25A12 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-11953R-CY7)
Dodavatel: Bioss
Popis: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11953R-HRP

Anti-SLC25A12 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-11953R-HRP)
Dodavatel: Bioss
Popis: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11953R-A750

Anti-SLC25A12/ARALAR Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-11953R-A750)
Dodavatel: Bioss
Popis: Calcium Signalling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signalling begins with Ca²⁺ entry in mitochondria via the Ca²⁺ uniporter followed by Ca²⁺ activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca²⁺-binding mitochondrial aspartate-glutamate carrier, has Ca²⁺ binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca²⁺ signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOADIAAM114E

Anti-Caspase-4 Mouse Monoclonal Antibody [clone: 4B9]

Katalogové číslo: (ENZOADIAAM114E)
Dodavatel: ENZO LIFE SCIENCES
Popis: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis.
Měrná jednotka: 1 * 100 µG

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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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