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CLF [Cholyl-Lys-Fluorescein]

Katalogové číslo: (AATB36701)

Dodavatel: AAT BIOQUEST

Popis: CLF is a fluorescein-labeled bile acid analog that closely parallels the cellular binding and uptake properties of cholic acid derivatives.

Měrná jednotka: 1 * 1 mg

Akce

N/A Each

Anti-AMACR Mouse Monoclonal Antibody

Katalogové číslo: (PRSI32-107)

Dodavatel: ProSci Inc.

Popis: AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Sodium cholate 99%

Dodavatel: Thermo Fisher Scientific

Popis: Sodium cholate 99%

Bezpečnostní list Certifikáty

Sodium cholate ≥98.5%, white powder

Dodavatel: MP Biomedicals

Popis: Cholic acid is a biochemical solubilizing agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.

Taurocholic acid sodium salt ≥97%, powder, Practical grade

Dodavatel: MP Biomedicals

Popis: Applications
Taurocholic Acid Sodium Salt is an anionic detergent used for protein solubilization.
Product Description
Taurocholic Acid Sodium Salt is the conjugation product of cholic acid with taurine and the principal constituent of the bile of carnivorous animals.
Biochem/physiol Actions
Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Melting Point: 230 °C (decomposes)(Lit.)
Presentation: White Powder
Format: Powder
pH: 6 - 7.5(1% aq soln)
Aggregation Number: 4
Critical Micelle Concentration (CMC): 3-11 mM
Heavy Metals: =20 ppm
Loss on Drying: =7.0%
NOTES: Sodium Cholate : =3.0%
Solubility: Soluble in water (100 mg/mL).
Storage & Handling: Store at Room Temperature (15-30 °C).