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Image Unavailable-BOSSBS-3596R-A488

Anti-SIAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-3596R-A488)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3596R-CY3

Anti-SIAH1 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-3596R-CY3)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.
Měrná jednotka: 1 * 100 µl

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Image Unavailable-BOSSBS-3596R-HRP

Anti-SIAH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-3596R-HRP)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3596R-CY5

Anti-SIAH1 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-3596R-CY5)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3596R-A680

Anti-SIAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-3596R-A680)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabiliser of SIAH1, facilitating the degradation of nuclear proteins.
Měrná jednotka: 1 * 100 µl
Product Image-AATB344

5(6)-Carboxyrhodamine 6G ethylenediamine ≥95%

Katalogové číslo: (AATB344)
Dodavatel: AAT BIOQUEST
Popis: 5(6)-Carboxyrhodamine 6G ethylenediamine is a building block for developing rhodamine bioconjugates.
Měrná jednotka: 1 * 1 mg
Image Unavailable-ENZOENZ42843

Gold 525 dUTP

Katalogové číslo: (ENZOENZ42843)
Dodavatel: ENZO LIFE SCIENCES
Popis: Gold 525 [5(6)-Carboxyrhodamine 6G] dUTP can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase. Fluorescently labelled probes can be prepared with this fluorescent nucleotide by a variety of methods including nick translation, random prime labelling, cDNA labelling and 3’-end labelling. Probes generated by these methods are suitable for use for the identification of specific sequences by in situ hybridization procedures on fixed cells and tissues by direct fluorescence detection. Gold 525 dUTP can also be used for multicolor fluorescence labelling.
Měrná jednotka: 1 * 25 Nmo

New Product


Product Image-AATB331

5-Carboxyrhodamine 6G (5-CR6G) single isomer ≥95%

Katalogové číslo: (AATB331)
Dodavatel: AAT BIOQUEST
Popis: 5-CR6G is the purified single isomer of 5(6)-CR6G.
Měrná jednotka: 1 * 10 mg
Product Image-AATB332

6-Carboxyrhodamine 6G (6-CR6G) single isomer ≥95%

Katalogové číslo: (AATB332)
Dodavatel: AAT BIOQUEST
Popis: 6-CR6G is the other purified single isomer of 5(6)-CR6G.
Měrná jednotka: 1 * 10 mg
Product Image-ABGEAP1303A

Anti-BCL2 Rabbit Polyclonal Antibody

Katalogové číslo: (ABGEAP1303A)
Dodavatel: Abgent
Popis: This apoptosis regulator Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-110 amino acids from human Bcl. Including factor-dependent lymphohematopoietic and neural cells this antibody suppresses apoptosis.
Měrná jednotka: 1 * 400 µl
Product Image-AATB343

5(6)-Carboxyrhodamine 6G cadaverine ≥95%

Katalogové číslo: (AATB343)
Dodavatel: AAT BIOQUEST
Popis: 5(6)-Caroxyrhodamine 6G cadaverine is a building block for developing rhodamine bioconjugates.
Měrná jednotka: 1 * 1 mg
Product Image-AATB346

6-Carboxyrhodamine 6G succinimidyl ester (6-CR6G SE) single isomer ≥90%

Dodavatel: AAT BIOQUEST
Popis: 6-CR6G, SE is amine-reactive derivative of 6-CR6G.

Image Unavailable-APOSBIPG1581-500MG

m-PEG3-Amine

Katalogové číslo: (APOSBIPG1581-500MG)
Dodavatel: Apollo Scientific
Popis: m-PEG3-Amine
Měrná jednotka: 1 * 500 mg
Product Image-AATB345

5-CR6G, SE single isomer ≥90%

Katalogové číslo: (AATB345)
Dodavatel: AAT BIOQUEST
Popis: 5-CR6G, SE is amine-reactive derivative of 5-CR6G.
Měrná jednotka: 1 * 5 mg
Image Unavailable-APOSBIPG1349-250MG

Bromo-PEG3-t-butyl ester

Dodavatel: Apollo Scientific
Popis: Bromo-PEG3-t-butyl ester

Image Unavailable-APOSBIPG1837-500MG

Thiol-PEG3-acid

Dodavatel: Apollo Scientific
Popis: Thiol-PEG3-acid

Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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