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Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.

Katalogové číslo: PRSI27-337

Měrná jednotka: 1 * 50 µG

Dodavatel: ProSci Inc.

Akce

Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.

Katalogové číslo: PRSI27-336

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: Replacement channel, 100 µl, yellow, Research® plus, Pro: Eppendorf Research® plus

Katalogové číslo: EPPE3122612.006

Měrná jednotka: 1 * 1 KS

Dodavatel: EPPENDORF

Akce

Popis: Power supply for single channel electronic pipettes, 240 V, 50 Hz (UK plug), Pro: Electronic pipettes, Matrix

Katalogové číslo: MATR6092

Měrná jednotka: 1 * 2 KS

Dodavatel: THERMO MATRIX TECHNOLOGIES

Akce

Popis: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Katalogové číslo: PRSI25-055

Měrná jednotka: 1 * 50 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU3F1 is a member of the POU domain family of proteins, and regulates events during neurogenesis and myelination.

Katalogové číslo: PRSI27-779

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes. Studies have cloned and sequenced cDNAs encoding a novel mouse POU domain protein, Oct-11, that is closely related within the POU domain to the POU class II proteins, Oct-1 and Oct-2.

Katalogové číslo: PRSI27-626

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU2F1 is a member of the POU family that represents the double-stranded DNA binding proteins specifically binding to the block C region.

Katalogové číslo: PRSI28-705

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU4F1 is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages.BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages (Gerrero et al., 1993).

Katalogové číslo: PRSI28-937

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.

Katalogové číslo: PRSI28-880

Měrná jednotka: 1 * 50 µG

Dodavatel: ProSci Inc.

Akce

Popis: Jednotka k testování těsnosti pipet PLT (Pipette Leak Tester) pro pipety na principu „vzduchového polštáře umožňuje denní kontrolu pipet a poskytuje záruku spolehlivosti pipetování mezi rutinními kalibracemi. Jednotka je schopná detekovat a vyčíslit i nejmenší netěsnosti.

Katalogové číslo: 613-1557

Měrná jednotka: 1 * 1 KS

Dodavatel: Brand

Akce

Popis: POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm

Katalogové číslo: PRSI31-236

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].

Katalogové číslo: PRSI27-318

Měrná jednotka: 1 * 50 µG

Dodavatel: ProSci Inc.

Akce

Popis: POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes.

Katalogové číslo: PRSI27-625

Měrná jednotka: 1 * 50 µG

Dodavatel: ProSci Inc.

Akce

Popis: Nástavec pro Pasteurovy pipety SI/PVC, QuikSip™

Katalogové číslo: 612-1907

Měrná jednotka: 1 * 1 KS

Dodavatel: Brand

Akce

Popis: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.

Katalogové číslo: PRSI55-446

Měrná jednotka: 1 * 400 µl

Dodavatel: ProSci Inc.

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