Hledali jste: 5-Fluoro-5\\\'-deoxyuridine+(Doxifluridine)

Katalogové číslo: (BSBTPA1030-1)

Dodavatel: Boster Bio

Popis: Rabbit IgG polyclonal antibody for Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Měrná jednotka: 1 * 0,1 mg

Akce

Katalogové číslo: (AATB17008)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17016)

Dodavatel: AAT BIOQUEST

Popis: The biotin-modified deoxyuridine 5'-triphosphates are widely used for a variety of non-radioactive DNA labeling reactions including nick translation, random prime labeling, cDNA labeling and 3'-end labeling.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17026)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17039)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Dodavatel: AAT BIOQUEST

Popis: Fluorescein-dT phosphoramidite provides a valuable tool to add the fluorescein tag to a desired location of an oligo sequence. For efficiently labeling an oligonucleotide.

Katalogové číslo: (AATB17029)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17040)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates are one of the most common methods to produce dye-labelled DNA via the conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17027)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.

Měrná jednotka: 1 * 25 Nmo

Akce

Katalogové číslo: (AATB17034)

Dodavatel: AAT BIOQUEST

Popis: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labelling or PCR.

Měrná jednotka: 1 * 100 Nmo

New Product Akce

Katalogové číslo: (PRSI92-088)

Dodavatel: ProSci Inc.

Popis: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield, length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI33-918)

Dodavatel: ProSci Inc.

Popis: Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI34-176)

Dodavatel: ProSci Inc.

Popis: It recognises a protein of 36 kDa, identified as Thymidylate Synthase (TS). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-219)

Dodavatel: ProSci Inc.

Popis: This antibody is specific for a protein of 36 kDa, identified as Thymidylate Synthase (TS). Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-744)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-768)

Dodavatel: ProSci Inc.

Popis: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

Měrná jednotka: 1 * 100 µG

New Product Akce