Hledali jste: 5,10,15,20-Tetra(4-pyridyl)porphyrin

Katalogové číslo: (APOSOR918293-1G)

Dodavatel: Apollo Scientific

Popis: Chloride ionophore I 97%

Měrná jednotka: 1 * 1 g

Akce

Katalogové číslo: (BOSSBS-7954R)

Dodavatel: Bioss

Popis: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP). AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Thermo Fisher Scientific

Popis: Hemin derived from porcine is an iron-containing prosthetic group present in some proteins and can be an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion.
Hemin is a protoporphyrin IX containing a ferric iron (Fe3+) ion with a coordinating chloride ligand

Bezpečnostní list

Katalogové číslo: (33738.ME)

Dodavatel: Thermo Fisher Scientific

Popis: Iron(III) meso-tetraphenylporphine-µ-oxo dimer

Měrná jednotka: 1 * 500 mg

Bezpečnostní list Certifikáty Akce

Dodavatel: Hach

Popis: Test kit, Porphyrin reagent 1

Dodavatel: Merck

Popis: Pyrrole is used as one of the building blocks of biochemical macrocycles such as chlorins, porphyrins and corrins. It is also used for many technologically relevel applications such as in organometallic complexes and precursor molecules for self-assembled monolayers on metal surfaces.

Katalogové číslo: (PRSI91-248)

Dodavatel: ProSci Inc.

Popis: Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).

Měrná jednotka: 1 * 50 µG

Akce

Dodavatel: MP Biomedicals

Popis: Porphobilinogen is a chromogen substance that is an intermediate in the biosynthesis of heme and porphyrins. It appears in the urine of people with porphyria, representing an error of metabolism.

Katalogové číslo: (PRSI29-613)

Dodavatel: ProSci Inc.

Popis: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI29-612)

Dodavatel: ProSci Inc.

Popis: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (SIAL252182-500MG)

Dodavatel: Merck

Popis: 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II), Sigma-Aldrich®

Měrná jednotka: 1 * 500 mg

Akce

Katalogové číslo: (SIAL252174-25MG)

Dodavatel: Merck

Popis: Zinc meso-tetraphenylporphine ≥94.0% low chlorine, Sigma-Aldrich®

Měrná jednotka: 1 * 25 mg

Akce

Katalogové číslo: (SIAL252190-500MG)

Dodavatel: Merck

Popis: Cobalt(II) meso-tetraphenylporphine ≥85% (dye content), Sigma-Aldrich®

Měrná jednotka: 1 * 500 mg

Akce

Katalogové číslo: (SIAL259071-500MG)

Dodavatel: Merck

Popis: Iron(III) meso-tetraphenylporphine chloride ≥94% (by HPLC), Sigma-Aldrich®

Měrná jednotka: 1 * 500 mg

Akce

Katalogové číslo: (SIAL252204-500MG)

Dodavatel: Merck

Popis: Nickel(II) meso-tetraphenylporphine ≥95% (dye content), Sigma-Aldrich®

Měrná jednotka: 1 * 500 mg

Akce

Dodavatel: Merck

Popis: Zinc meso-tetraphenylporphine ≥97.5%, Sigma-Aldrich®