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Product Image-ELTN726661/42

ESD Safety sandals, Velcro® fastening, Trainers, Scott Pro

Dodavatel: ELTEN
Popis: 100% metal- and leather-free, lightweight ESD safety sandal made from microfibre and textile upper, a padded tongue plus a slip-resistant, dual-density TPU/PU sole (Trainers).

Environmentally Preferable

Image Unavailable-ELTN721331/44

ESD Safety Shoes, Lacing Sytem, Ian XXTP Pro Boa® Low S3 S

Dodavatel: ELTEN
Popis: ESD safety shoe is made from hydrophobised microfibre/hydrophobised textile upper and a TPU/PU sole (Wellmaxx Trainers Power). Sole core made of Infinergy® by BASF

Environmentally Preferable New Product

Image Unavailable-BOSSBS-1070R-FITC

Anti-NPY1R Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-1070R-FITC)
Dodavatel: Bioss
Popis: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY >[Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY >NPY (2-36) >[Ile-31, Gln-34] PP and PYY (3-36) >PP >NPY free acid.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1070R-A488

Anti-NPY1R Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-1070R-A488)
Dodavatel: Bioss
Popis: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY >[Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY >NPY (2-36) >[Ile-31, Gln-34] PP and PYY (3-36) >PP >NPY free acid.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2044R-A680

Anti-LOX 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-2044R-A680)
Dodavatel: Bioss
Popis: Receptor that mediates the recognition, internalisation and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
Měrná jednotka: 1 * 100 µl
Image Unavailable-APOSPC201261-250MG

(S)-4,4-Difluoropyrrolidine-2-carboxylic acid 95+%

Dodavatel: Apollo Scientific
Popis: (S)-4,4-Difluoropyrrolidine-2-carboxylic acid 95+%

Image Unavailable-BOSSBS-1346R-CY5

Anti-TRP73 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-1346R-CY5)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5809R-A488

Anti-LGALS7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-5809R-A488)
Dodavatel: Bioss
Popis: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5809R-FITC

Anti-LGALS7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-5809R-FITC)
Dodavatel: Bioss
Popis: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0059R-A750

Anti-APAF1 (NT) Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-0059R-A750)
Dodavatel: Bioss
Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOADI905185100

Anti-BNIP3L Rabbit Polyclonal Antibody

Katalogové číslo: (ENZOADI905185100)
Dodavatel: ENZO LIFE SCIENCES
Popis: Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. In particular, Bnip3L interacts with and overcomes the suppression of apoptosis mediated by Bcl-2 and Bcl-xL.
Měrná jednotka: 1 * 100 µG
Product Image-114-7729

ESD safety shoes, lace-up, Dimension Pro, Horizon Low

Dodavatel: ELTEN
Popis: Leather-free, anti-slip ESD safety shoes made from hydrophobised microfibre and hydrophobised CORDURA® (tear and abrasion resistant, dirt and water repellent) upper, a full padded bellows tongue plus a slip resistant, dual-density TPU/PU sole (Dimension Pro).

Environmentally Preferable

Product Image-ACRO459110050

Pyrrolidine-3-carboxylic acid 98%

Dodavatel: Thermo Fisher Scientific
Popis: Pyrrolidine-3-carboxylic acid 98%

Image Unavailable-BOSSBS-3363R-CY5

Anti-RPS6KA1 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-3363R-CY5)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity. Phosphorylates RPS6 in response to serum or EGF via an mTOR-independent mechanism and promotes translation initiation by facilitating assembly of the preinitiation complex. In response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation. Is involved in the mTOR nutrient-sensing pathway by directly phosphorylating TSC2 at 'Ser-1798', which potently inhibits TSC2 ability to suppress mTOR signaling, and mediates phosphorylation of RPTOR, which regulates mTORC1 activity and may promote rapamycin-sensitive signaling independently of the PI3K/AKT pathway. Mediates cell survival by phosphorylating the pro-apoptotic proteins BAD and DAPK1 and suppressing their pro-apoptotic function. Promotes the survival of hepatic stellate cells by phosphorylating CEBPB in response to the hepatotoxin carbon tetrachloride (CCl4).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3364R-CY5.5

Anti-RPS6KA1 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-3364R-CY5.5)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity. Phosphorylates RPS6 in response to serum or EGF via an mTOR-independent mechanism and promotes translation initiation by facilitating assembly of the preinitiation complex. In response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation. Is involved in the mTOR nutrient-sensing pathway by directly phosphorylating TSC2 at 'Ser-1798', which potently inhibits TSC2 ability to suppress mTOR signaling, and mediates phosphorylation of RPTOR, which regulates mTORC1 activity and may promote rapamycin-sensitive signaling independently of the PI3K/AKT pathway. Mediates cell survival by phosphorylating the pro-apoptotic proteins BAD and DAPK1 and suppressing their pro-apoptotic function. Promotes the survival of hepatic stellate cells by phosphorylating CEBPB in response to the hepatotoxin carbon tetrachloride (CCl4).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3364R-A647

Anti-RPS6KA1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-3364R-A647)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity. Phosphorylates RPS6 in response to serum or EGF via an mTOR-independent mechanism and promotes translation initiation by facilitating assembly of the preinitiation complex. In response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation. Is involved in the mTOR nutrient-sensing pathway by directly phosphorylating TSC2 at 'Ser-1798', which potently inhibits TSC2 ability to suppress mTOR signaling, and mediates phosphorylation of RPTOR, which regulates mTORC1 activity and may promote rapamycin-sensitive signaling independently of the PI3K/AKT pathway. Mediates cell survival by phosphorylating the pro-apoptotic proteins BAD and DAPK1 and suppressing their pro-apoptotic function. Promotes the survival of hepatic stellate cells by phosphorylating CEBPB in response to the hepatotoxin carbon tetrachloride (CCl4).
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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